LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-TRAIL-R3 / DCR1 Antibody (clone 2B8, RPE) LS-C58141

Note: This antibody replaces LS-C58142


Wt. Vol. Conc. Price
- 100 tst - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TRAIL-R3 / DCR1 Antibodies

Anti-TRAIL-R3 / DCR1 Antibody (clone DJR3, PE) LS-C106229
Mouse Monoclonal [clone DJR3] (IgG1,k) to Human TRAIL-R3 / DCR1
Flow Cytometry
PE Conjugated
Flow Cytometry Image
Anti-TRAIL-R3 / DCR1 Antibody (aa1-280, clone TRAIL-R3-02) LS-C355225
Mouse Monoclonal [clone TRAIL-R3-02] (IgG1) to Human TRAIL-R3 / DCR1
Flow Cytometry

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2B8] (IgG1) to Human TRAIL-R3 / DCR1
Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
RPE Conjugated


Human TRAIL-R3 / DCR1
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2B8]
R. Phycoerythrin
Affinity purified


  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:10)
  • (applications tested for the base form of this product only)

Specificity and Use

TRAIL-R3 / DCR1 antibody was raised against dcR1-Fc Chimeric protein.
Recognizes human CD263, a 60 Kd cell surface protein, which is otherwise known as decoy receptor 1 (DcR1). CD263 is a member of the tumor necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumor cells. Does not inhibit DcR1 (CD263) inhibitory function in TRAIL-induced apoptosis.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.


Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
+4°C, avoid freezing
For research use only.

About TRAIL-R3 / DCR1

O14798 NM_003841 NP_003832.2

TNFRSF10C Antibody, CD263 antigen Antibody, CD263 Antibody, Cytotoxic TRAIL receptor-3 Antibody, Decoy receptor 1 Antibody, DCR1 Antibody, DCR1-TNFR Antibody, LIT Antibody, Lymphocyte inhibitor of TRAIL Antibody, TRAIL-R3 Antibody, TRAILR3 Antibody, TRAIL receptor 3 Antibody, TRID Antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD.

Flow Cytometry

Flow Cytometry
Human Granulocytes stained with Mouse anti-Human CD263 (LS-C44964). This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.

Requested From: United States
Date Requested: 10/27/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number