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Human TRA2B / SFRS10 | |
Rabbit | |
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken (tested or 100% immunogen sequence identity) | |
IgG Polyclonal | |
Unconjugated | |
Immunoaffinity purified | |
Unmodified |
TRA2B / SFRS10 antibody was raised against synthetic peptide: RSYSRDYRRRHSHS (KLH). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Turkey, Chicken, Platypus, Lizard (100%); Opossum (93%); Xenopus (86%). | |
Recognizes human Splicing Factor, Arginine/Serine-Rich 10. Species cross-reactivity: rodent. | |
Suitable for use in ELISA and Immunohistochemistry. ELISA (serum titer): 1:112000. Predicted Molecular Weight: 33.67kD. |
PBS, pH 7.2, sodium azide, 40% glycerol. | |
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles. | |
For research use only. |
TRA2B Antibody, Htra2-beta Antibody, SRFS10 Antibody, TRA2-BETA Antibody, TRAN2B Antibody, SFRS10 Antibody, TRA-2 beta Antibody
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.