LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
TPSAB1 / Mast Cell Tryptase Antibody (clone AA1) IHC‑plus™ LS‑B2347
Note: This antibody replaces LS-C11537, LS-C43604
Mast Cell Tryptase antibody LS-B2347 is an unconjugated mouse monoclonal antibody to Mast Cell Tryptase (TPSAB1) from human, rat, cat and other species. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2347-50
50 µg (1 mg/ml)
Unavailable

Popular TPSAB1 / Mast Cell Tryptase Products

Antibody
Species: Mouse
Applications: Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Antibody
Species: Mouse
Applications: Western blot, Immunoprecipitation, ELISA, Neutralization
Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cell. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2357 concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Cat, Dog
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2478 concentration 5 ug/ml.
Species: Human, Monkey, Cat, Dog
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA

Product Description

Mast Cell Tryptase antibody LS-B2347 is an unconjugated mouse monoclonal antibody to Mast Cell Tryptase (TPSAB1) from human, rat, cat and other species. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About TPSAB1 / Mast Cell Tryptase
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. Q15661 NM_003294 NP_003285.2

TPSAB1 Antibody, Alpha tryptase Antibody, Mast cell alpha II tryptase Antibody, Tryptase alpha-1 Antibody, Tryptase beta I Antibody, Tryptase-III Antibody, TPSB1 Antibody, Tryptase alpha II Antibody, TPS1 Antibody, TPS2 Antibody, Tryptase beta-1 Antibody, Tryptase-1 Antibody, Tryptase-I Antibody, Mast cell beta I tryptase Antibody, Tryptase alpha/beta 1 Antibody, Tryptase alpha/beta-1 Antibody, Tryptase beta 1 Antibody, Tryptase I Antibody


Specifications

Target
Human TPSAB1 / Mast Cell Tryptase
Host
Mouse
Reactivity
Human, Monkey, Rat, Cat, Dog (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [AA1]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • IHC - Frozen
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human mast cell tryptase purified from human lung tissue.
Specificity
Recognizes human mast cell tryptase, both isoforms. Is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology. Tryptases are the products of a number of and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction.
Usage
Immunohistochemistry: LS-B2347 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2347 was determined to be 2.5 ug/ml. Histology Positive Control Tissue: Tonsil.
Presentation
PBS, pH 7.4, 0.09% sodium azide.
Storage
4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Immunohistochemistry

Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.
Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.

Immunohistochemistry

Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.
Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.

Immunohistochemistry

Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.
Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.

Immunohistochemistry

Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.
Anti-TPSAB1 / Mast Cell Tryptase antibody IHC of human breast, mast cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2347 concentration 5 ug/ml.


Requested From: 
Date Requested: 6/19/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number