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Anti-TPP1 / CLN2 Antibody (aa66-324) LS-C186299

See our new TPP1 / CLN2 ELISA Kits
Human TPP1 / CLN2 ELISA Kit - LS-F7814
Mouse TPP1 / CLN2 ELISA Kit - LS-F8654
(kits do not necessarily contain the antibody listed on this page)


Wt. Vol. Conc. Price
- 100 µl 0.64 mg/ml $335

LSBio (Direct) LSBio (Direct)

TPP1 / CLN2 Antibody LS-C186299 Images

[click image for a larger image and more details]
IHC of paraffin-embedded SW480 xenograft using TPP1 antibody at 1:100 dilution.
Immunofluorescence of methanol-fixed A431 using TPP1 antibody at 1:200 dilution.
Western blot
Sample (30 ug of whole cell lysate).

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Rabbit Polyclonal (IgG) to Human TPP1 / CLN2
IHC - Paraffin, ICC, Western blot


Human TPP1 / CLN2
Human (tested or 100% immunogen sequence identity)
Bovine, Dog (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


IHC - Paraffin (1:100 - 1:1000), ICC (1:100 - 1:1000), Western blot (1:500 - 1:3000)

Specificity and Use

TPP1 / CLN2 antibody was raised against recombinant fragment corresponding to a region within amino acids 66 and 324 of TPP1 (SwissProt O14773). Percent identity by BLAST analysis: Human (100%); Dog, Bovine (91%); Mouse (87%); Rat (86%).
Human TPP1 / CLN2
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).


0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About TPP1 / CLN2

O14773 NM_000391 NP_000382.3

TPP1 Antibody, CLN2 Antibody, GIG1 Antibody, LPIC Antibody, LINCL Antibody, TPP-I Antibody, Tripeptidyl aminopeptidase Antibody, Tripeptidyl peptidase I Antibody, Tripeptidyl-peptidase 1 Antibody, Tripeptidyl-peptidase I Antibody, TPP-1 Antibody, Growth-inhibiting protein 1 Antibody

TPP1 / CLN2 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification.


IHC of paraffin-embedded SW480 xenograft using TPP1 antibody at 1:100 dilution.


Immunofluorescence of methanol-fixed A431 using TPP1 antibody at 1:200 dilution.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: A431 , B: H1299, C: Hela. 7.5% SDS PAGE. TPP1 antibody diluted at 1:1000.

Requested From: United States
Date Requested: 10/7/2015

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