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Anti-TPMT Antibody (Biotin) LS-C211223

Ordering

Wt. Vol. Conc. Price
100 µg - - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TPMT Antibodies

Anti-TPMT Antibody (aa1-246, Biotin) LS-C283528
Mouse Monoclonal (IgG1) to Human TPMT
Human
IHC, ICC, Western blot, ELISA
Biotin Conjugated
Anti-TPMT Antibody IHC-plus™ LS-B10634
Rabbit Polyclonal (IgG) to Human TPMT
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TPMT Antibody (aa200-250) IHC-plus™ LS-B14110
Rabbit Polyclonal to Human TPMT
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TPMT
Human
IHC, IHC - Paraffin, Western blot, ELISA (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human TPMT
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Biotin. Also available Unconjugated or conjugated with HRP, FITC.
Caprylic acid and ammonium sulfate precipitation
Unmodified

Applications

  • IHC
  • IHC - Paraffin
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)

Specificity and Use

TPMT antibody was raised against recombinant human Thiopurine S-methyltransferase protein.
Human TPMT
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
For research use only.

About TPMT

P51580 NM_000367 NP_000358.1

TPMT Antibody, Thiopurine S-methyltransferase Antibody, Thiopurine methyltransferase Antibody

TPMT is the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

Immunohistochemistry

Immunohistochemistry
Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10634 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Western blot of Thiopurine S-methyltransferase antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 27 kDa. Observed band size: 27 kDa Additional bands at: 90 kDa, 100 kDa. We are unsure as to the identity of these extra bands. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/8/2016

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