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TPMT

thiopurine S-methyltransferase

TPMT is the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

Gene Name: thiopurine S-methyltransferase
Synonyms: TPMT, Thiopurine S-methyltransferase, Thiopurine methyltransferase
Target Sequences: NM_000367 NP_000358.1 P51580

☰ Filters
Antibodies (43)
ELISA Kits (8)
Proteins (6)
Custom (4)
Over-Expression Lysate (2)
Primary (43)
Recombinant (4)
Sandwich (4)
TPMT (57)
Human (47)
Mouse (16)
Rat (4)
Dog (3)
Pig (3)
IHC (17)
IHC-P (9)
WB (40)
Flo (2)
ELISA (15)
ICC (1)
IF (8)
Peptide-ELISA (1)
rabbit (33)
mouse (10)
Product Group
IHCPlus (1)
IgG (18)
IgG1 (8)
IgG1,k (2)
monoclonal mc (10)
polyclonal pc (33)
1B5 (1)
AT2E7 (1)
OTI2A2 (2)
OTI4B1 (2)
OTI4C1 (2)
OTI5B4 (2)
96-Well Strip Plate (8)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Carrier-free (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (27)
aa26-227 (8)
aa152-201 (4)
N-Terminus (1)
aa200-250 (1)
No (57)
Plasma (4)
Serum (4)
Tissue Homogenates (1)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
TPMT Antibody - Immunoperoxidase of monoclonal antibody to TPMT on formalin-fixed paraffin-embedded human spleen. [antibody concentration 1 ug/ml]
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TPMT Mouse anti-Human Monoclonal (1B5) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
TPMT Antibody - IHC of paraffin-embedded breast tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (OTI2A2) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
TPMT Antibody - IHC of paraffin-embedded breast tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (Carrier-free) (OTI2A2) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TPMT Antibody - IHC of paraffin-embedded liver tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (OTI4C1) Antibody
Dog, Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
TPMT Antibody - IHC of paraffin-embedded liver tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (Carrier-free) (OTI4C1) Antibody
Dog, Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TPMT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TPMT Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TPMT Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
TPMT Antibody - Anti-TPMT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TPMT Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
TPMT Antibody - IHC of paraffin-embedded Kidney tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (OTI5B4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TPMT Antibody - IHC of paraffin-embedded Kidney tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (Carrier-free) (OTI5B4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TPMT Antibody - Immunofluorescence analysis of U2OS cells using TPMT antibody. Blue: DAPI for nuclear staining.
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TPMT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TPMT ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$834
TPMT Antibody - IHC of paraffin-embedded colon tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
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TPMT Mouse anti-Human Monoclonal (OTI4B1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
TPMT Antibody - IHC of paraffin-embedded colon tissue using anti-TPMT mouse monoclonal antibody. (Dilution 1:50).
Select
TPMT Mouse anti-Human Monoclonal (Carrier-free) (OTI4B1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TPMT Antibody - Immunofluorescent analysis of TPMT staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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TPMT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
TPMT Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TPMT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
TPMT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
TPMT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
TPMT Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using TPMT Polyclonal Antibody at dilution of 1:60(×200)
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TPMT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TPMT Antibody - Western blot of TPMT pAb in extracts from K562 cells and mouse liver, kidney tissues.
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TPMT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
TPMT Antibody - Western Blot: The cell lysates (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TPMT antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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TPMT Mouse anti-Human Monoclonal (AT2E7) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
Select
TPMT Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
Select
TPMT Rabbit anti-Human Polyclonal (aa200-250) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
Select
TPMT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$582
Viewing 1-25 of 57 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).