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TPH2

tryptophan hydroxylase 2

TPH2 encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Gene Name: tryptophan hydroxylase 2
Synonyms: TPH2, ADHD7, NTPH, Tryptophan hydroxylase 2, Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2
Target Sequences: NM_173353 NP_775489.2 Q8IWU9

Publications (1)

1
Activation of glucagon-like peptide-1 receptors reduces the acquisition of aggression-like behaviors in male mice. Jesper Vestlund, Qian Zhang, Olesya T Shevchouk, Daniel Hovey, Lundström Sebastian, Lars Westberg, Elisabet Jerlhag. Translational psychiatry. 2022 October;12:445. [Full Text Article] [PubMed:36229445] [PMC:PMC9561171] Related Antibodies: LS-C346253.

☰ Filters
Antibodies (52)
ELISA Kits (9)
Proteins (5)
Cell-Based (1)
Custom (2)
Primary (52)
Recombinant (5)
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TPH2 (66)
Human (47)
Mouse (26)
Rat (20)
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Bovine (6)
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Chimpanzee (6)
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Gibbon (6)
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ELISA (15)
ICC (1)
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rabbit (49)
goat (3)
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polyclonal pc (52)
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aa1-138 (8)
aa168-193 (7)
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aa16-29 (1)
aa33-45 (1)
aa43-56 (1)
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No (65)
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TPH2 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
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TPH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TPH2 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using TPH2 Antibody at dilution of 1:100
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TPH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
TPH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
TPH2 Antibody
Select
TPH2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
TPH2 Antibody - TPH2 Antibody IHC of formalin-fixed and paraffin-embedded mouse brain followed by peroxidase-conjugated secondary antibody and DAB staining.
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TPH2 Rabbit anti-Human Polyclonal (aa168-193) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TPH2 Antibody - TPH2 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TPH2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
TPH2 Rabbit anti-Human Polyclonal (aa168-193) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
TPH2 Rabbit anti-Human Polyclonal (aa168-193) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
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TPH2 Rabbit anti-Human Polyclonal (aa168-193) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
TPH2 Rabbit anti-Human Polyclonal (aa168-193) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
TPH2 Rabbit anti-Human Polyclonal (aa168-193) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
TPH2 Rabbit anti-Human Polyclonal (aa168-193) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
TPH2 Antibody - Tryptophan hydroxylase 2 / TPH2 antibody (4µg/ml) staining of paraffin embedded Human Brain Stem. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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TPH2 Goat anti-Human Polyclonal (aa43-56) Antibody
Human
IF, IHC, Peptide-ELISA
Unconjugated
100 µg/$503
TPH2 Antibody - Western blot analysis of extracts from HeLa, Cos7 and 293 cells, using TPH2 (Ab-19) antibody.
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TPH2 Rabbit anti-Human Polyclonal (p19) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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TPH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TPH2 Antibody - Western blot of Phospho-TPH2 (S19) antibody
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TPH2 Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TPH2 Antibody - Western blot of TPH2 antibody
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TPH2 Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TPH2 Antibody - Western blot analysis of extracts from HepG2 cells, using TPH2 (Phospho-Ser19) antibody.
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TPH2 Rabbit anti-Human Polyclonal (pSer19) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
TPH2 Antibody - Western blot analysis of the lysates from HUVECcells using TPH2 antibody.
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TPH2 Rabbit anti-Human Polyclonal (aa13-62) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TPH2 Antibody - Western blot analysis of TPH2 using MCF-7 whole cells lysates
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TPH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TPH2 Antibody - Goat Anti-Tph2 (mouse) Antibody (0.5µg/ml) staining of paraffin embedded Mouse Brain stem in sagittal (left) and coronal (right) sections of Raphe nuclei. Detection Alexa 594. Data obtained from Prof. D Crane, Griffith Univeristy, Brisbane, Australia
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TPH2 Goat anti-Mouse Polyclonal (aa33-45) Antibody
Mouse
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
TPH2 Antibody - TPH2 antibody (0.5 ug/ml) staining of HEK293 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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TPH2 Goat anti-Human Polyclonal (aa16-29) Antibody
Guinea pig, Horse, Bat, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
TPH2 Antibody - Western blot of TPH2 antibody.
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TPH2 Rabbit anti-Mouse Polyclonal (aa1-138) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
Select
TPH2 Rabbit anti-Human Polyclonal (Ser19) Antibody
Human
WB
Unconjugated
100 µl/$810
TPH2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TPH2 Rabbit anti-Human Polyclonal (aa55-104) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 66 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).