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Anti-TPH1 / Tryptophan Hydroxylase Antibody (phospho-Ser19) LS-C61881

Catalog	Size	Price
LS-C61881-100	100 µl	Unavailable

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Anti-TPH1 / Tryptophan Hydroxylase Antibody (N-Terminus) LS-C413050

Antibody:	Rabbit Polyclonal to Human TPH1 / Tryptophan Hydroxylase
Reactivity:	Human, Mouse, Rat, Rabbit, Chicken
Application:	IHC - Paraffin, ICC, Immunofluorescence, Western blot
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Antibody:	Rabbit Polyclonal to Rat TPH1 / Tryptophan Hydroxylase
Reactivity:	Rat, Mouse, Bovine
Application:	Western blot
Format:	Unconjugated

Details

Target:	Rat TPH1 / Tryptophan Hydroxylase
Host:	Rabbit
Reactivity:	Rat, Mouse, Bovine (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot (1:1000)

Specificity and Use

Immunogen:	Phosphopeptide corresponding to amino acid residues surrounding the phosphoSer19 of rat tryptophan hydroxylase 2 (TPH2).
Epitope:	pSer19
Specificity:	Specific for the ~55k tryptophan hydroxylase protein phosphorylated at Ser19

Packaging

Presentation:	50 uL of 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Storage:	Long term: -20°C; Short term: -20°C
Restrictions:	For research use only.

About TPH1 / Tryptophan Hydroxylase

Uniprot: P17752 NCBI: NM_004179 NP_004170.1

Synonyms: TPH1 Antibody, L-tryptophan hydroxylase Antibody, TRPH Antibody, Tryptophan 5-hydroxylase 1 Antibody, Tryptophan 5-monooxygenase 1 Antibody, TPRH Antibody, Tryptophan hydroxylase 1 Antibody, TPH Antibody

Description: TPH1 / TPH encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

(More About TPH1 / Tryptophan Hydroxylase)

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Western blot

Western blot of recombinant tryptophan hydroxylase incubated in the absence (Control) and presence of Ca2+/calmodulin dependent kinase II (CaMKII) showing specific immunolabeling of the ~55k tryptophan hydroxylase protein phosphorylated at Ser19.

Western blot

Requested From:
Date Requested: 8/17/2017

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