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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TPH1 / Tryptophan Hydroxylase Antibody IHC‑plus™ LS‑B7709
Note: This antibody replaces LS-C225
Tryptophan Hydroxylase antibody LS-B7709 is an unconjugated sheep polyclonal antibody to Tryptophan Hydroxylase (TPH1) from human, rat, mammal and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7709-50
50 µl
Unavailable

Popular TPH1 / Tryptophan Hydroxylase Products

Antibody
Species: Human, Rat
Applications: IHC, IHC - Frozen, Western blot
IHC of paraffin-embedded human brain tissue, using Tryptophan Hydroxylase (Ab-260) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-TPH1 / TPH antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7001 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: IHC, ICC, Western blot

Product Description

Tryptophan Hydroxylase antibody LS-B7709 is an unconjugated sheep polyclonal antibody to Tryptophan Hydroxylase (TPH1) from human, rat, mammal and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About TPH1 / Tryptophan Hydroxylase
TPH1 / TPH encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others. P17752 NM_004179 NP_004170.1

TPH1 Antibody, L-tryptophan hydroxylase Antibody, TRPH Antibody, Tryptophan 5-hydroxylase 1 Antibody, Tryptophan 5-monooxygenase 1 Antibody, TPRH Antibody, Tryptophan hydroxylase 1 Antibody, TPH Antibody


Specifications

Target
Rabbit TPH1 / Tryptophan Hydroxylase
Host
Sheep
Reactivity
Rabbit, Human, Rat, Mammal (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • IHC - Frozen (1:1000)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE.
Specificity
Specific for the ~55k tryptophan hydroxylase protein
Presentation
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug BSA per ml, 50% glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.
Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.

Western blot

Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.
Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.

Immunohistochemistry

Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.
Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.

Western blot

Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.
Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.

Immunohistochemistry

Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.
Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.

Western blot

Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.
Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.

Immunohistochemistry

Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.
Anti-TPH1 / TPH antibody IHC of adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7709 dilution 1:100.

Western blot

Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.
Western blot of human dorsal Raphe nucleus showing specific immunolabeling of the ~55k tryptophan hydroxylase protein.


Requested From: 
Date Requested: 6/25/2018

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