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TPH1 / Tryptophan Hydroxylase
tryptophan hydroxylase 1
TPH1 / TPH encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
| Gene Name: | tryptophan hydroxylase 1 |
| Family/Subfamily: | Monooxygenase |
| Synonyms: | TPH1, L-tryptophan hydroxylase, TRPH, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPRH, Tryptophan hydroxylase 1, TPH |
| Target Sequences: | NM_004179 NP_004170.1 P17752 |
Publications (1)
1
Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer. Hallett RM, Girgis-Gabardo A, Gwynne WD, Giacomelli AO, Bisson JN, Jensen JE, Dvorkin-Gheva A, Hassell JA. Oncotarget. 2016 7:53137-53152. (WB; Human)
[Full Text Article]
[PubMed:27447971]
[PMC:PMC5288174]
Related Antibodies: LS-C117936.
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TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (aa231-280) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Neuroscience
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (aa26-75) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Neuroscience
TPH1 / Tryptophan Hydroxylase Sheep anti-Rabbit Polyclonal Antibody
Rabbit, Rat, Mammal, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µl/$440
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (pSer58) Antibody
Chicken, Rabbit, Mouse, Rat, Human
IHC, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Rabbit, Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (40-120 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (200-280 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (Ser40) Antibody
Human
ICC, IHC, WB
Unconjugated
100 µl/$907
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (40-120 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (aa35-62) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TPH1 / Tryptophan Hydroxylase Sheep anti-Human Polyclonal Antibody
Human
IHC-Fr, WB
Unconjugated
0.1 ml/$579
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (p58) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (p260) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (Val256) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (Lys54) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (Ser31) Antibody
Human
ICC, IHC, WB
Unconjugated
100 µl/$810
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal Antibody
Human
ICC, IHC, WB
Unconjugated
100 µl/$810
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (pSer260) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TPH1 / Tryptophan Hydroxylase Rabbit anti-Human Polyclonal (pSer58) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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