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Anti-TPC2 / TPCN2 Antibody (aa735-747) IHC-plus™ LS-B4183

Note: This antibody replaces LS-C108409
Catalog Size Price
LS-B4183-50 50 µg (0.5 mg/ml) Unavailable

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4 TPC2 / TPCN2 Antibodies

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Anti-TPC2 / TPCN2 Antibody (aa727-740) LS-C3240
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Anti-TPC2 / TPCN2 Antibody (aa240-252) LS-C3241
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Anti-TPC2 / TPCN2 Antibody (aa700-752) LS-C95186
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Anti-TPC2 / TPCN2 Antibody (aa735-747) IHC-plus™ LS-B4183
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Immunohistochemistry Image
Anti-TPC2 / TPCN2 Antibody (N-Terminus) LS-C178859
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100% Guaranteed
Goat Polyclonal to Human TPC2 / TPCN2
Human
IHC - Paraffin
Unconjugated

Details

Human TPC2 / TPCN2
Goat
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (3.75 µg/ml)

Specificity and Use

TPC2 / TPCN2 antibody was raised against synthetic peptide C-EDELTERLSQHPH from the C-terminus of human TPCN2 (NP_620714.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (85%).
LS-E27163 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B4183. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa735-747
Human TPCN2.
Immunohistochemistry: LS-B4183 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B4183 was determined to be 3.75 ug/ml

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About TPC2 / TPCN2

Q8NHX9 AY029200 AAK31802.1

TPCN2 Antibody, TPC2 Antibody, Two pore segment channel 2 Antibody, SHEP10 Antibody

TPC2 / TPCN2 is a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.

Immunohistochemistry

Immunohistochemistry
Anti-TPCN2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4183 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-TPCN2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4183 concentration 3.75 ug/ml.

Requested From: 
Date Requested: 10/23/2017

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