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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TP73 / p73 Antibody (aa450‑636) LS‑C17142
P73 antibody LS-C17142 is an unconjugated rabbit polyclonal antibody to human p73 (TP73). Validated for IHC, IP and WB.
Antibody
Catalog
Size
Price
LS-C17142-100
100 µg
$605

Popular TP73 / p73 Products

Anti-p73 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2086 concentration 5 ug/ml.
Species: Human, Mouse
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Anti-p73 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2085 concentration 5 ug/ml.
Species: Human, Monkey
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Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Immunofluorescence, Western blot
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, Western blot, Immunoprecipitation
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

P73 antibody LS-C17142 is an unconjugated rabbit polyclonal antibody to human p73 (TP73). Validated for IHC, IP and WB.

Specifications

Target
Human TP73 / p73
Synonyms
TP73, p53-like transcription factor, p73, p53-related protein, Tumor protein p73
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
TP73 / p73 antibody was raised against gST fusion protein that contains aa450-636 of the p73 protein.
Epitope
aa450-636
Specificity
Recognizes amino acids 450-636 of human p73 protein. This region is common to both p73 alpha and p73 beta isoforms, hence both isoforms of the p73 protein will be detected.
Usage
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot: 1 ug/ml of the antibody will detect p73 in 30 ug of total cell lysate from overexpressing cell lines. Higher levels of antibody may be necessary when using native tissue sources. Immunohistochemistry: It may be necessary to incorporate a signal amplification technique in conjunction with standard procedures.
Presentation
PBS, pH 7.4, 0.05% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About TP73 / p73
This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. O15350 NM_005427 NP_005418.1


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Requested From: United States
Date Requested: 10/16/2018

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