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TP53BP2 / ASPP2

tumor protein p53 binding protein, 2

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Gene Name: tumor protein p53 binding protein, 2
Synonyms: TP53BP2, 53BP2, p53-binding protein 53bp2, p53BP2, PPP1R13A, ASPP2, BBP, BCL2-binding protein, p53-binding protein 2
Target Sequences: NM_005426 NP_005417.1 Q13625

☰ Filters
Antibodies (26)
Proteins (3)
Over-Expression Lysate (2)
Primary (26)
Recombinant (1)
TP53BP2 / ASPP2 (29)
Human (26)
Mouse (12)
Rat (6)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (11)
IHC-P (6)
WB (24)
ELISA (11)
IF (2)
IP (2)
Peptide-ELISA (1)
rabbit (25)
mouse (1)
Product Group
IHCPlus (1)
IgG (22)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (25)
3F8 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
aa93-122 (7)
aa133-182 (4)
aa825-875 (2)
Ser698 (1)
aa360-600 (1)
aa425-475 (1)
No (29)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
TP53BP2 / ASPP2 Antibody - Anti-TP53BP2 / ASPP2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa133-182) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
TP53BP2 / ASPP2 Antibody - Anti-TP53BP2 / ASPP2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa133-182) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
TP53BP2 / ASPP2 Antibody - Anti-TP53BP2 / ASPP2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa133-182) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
TP53BP2 / ASPP2 Antibody - Anti-TP53BP2 / ASPP2 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa133-182) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
TP53BP2 / ASPP2 Antibody - TP53BP2 monoclonal antibody (M01), clone 3F8 Western blot of TP53BP2 expression in HepG2.
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TP53BP2 / ASPP2 Mouse anti-Human Monoclonal (3F8) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$423
TP53BP2 / ASPP2 Antibody - Immunohistochemistry of paraffin-embedded Rat brain using TP53BP2 Polyclonal Antibody at dilution of 1:100 (40x lens).
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
TP53BP2 / ASPP2 Antibody - Detection of Human and Mouse ASPP2 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti-ASPP2 used at a dilution of 1:5000 (0.2 ug/ml ) and 1:1000 (1 ug/ml).
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa825-875) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$456
TP53BP2 / ASPP2 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using TP53BP2 Polyclonal Antibody at dilution of 1:35.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TP53BP2 / ASPP2 Antibody - Immunofluorescence analysis of A549 cells.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TP53BP2 / ASPP2 Antibody - Anti-ASPP2 Antibody - Western Blot. Western blot of Protein A purified anti-ASPP2 to detect over-expressed ASPP2 in MCF-7 cells (Lane 2, arrowhead). Lane 1 is a nontransfected control. Lane 3 is MCF-7 cells over-expressing ASPP1. Cell extracts were electrophoresed and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:1000 dilution. The identity of the lower MW band at approximately 40kD is unknown. Personal Communication, H. Yang, Univ. Oklahoma, Oklahoma City, OK.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$567
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
TP53BP2 / ASPP2 Antibody - Detection of Human ASPP2 by Immunohistochemistry. Sample: FFPE section of human prostate adenocarcinoma. Antibody: Affinity purified rabbit anti-ASPP2 used at a dilution of 1:500. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa825-875) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
100 µl/$470
TP53BP2 / ASPP2 Antibody - Western blot. All lanes: TP53BP2 antibody at 2 ug/ml+mouse thymus. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 126 kDa. Observed band size: 126 kDa.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa360-600) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$294; 100 µl/$360
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa425-475) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
TP53BP2 / ASPP2 Antibody - Western blot analysis of ASPP2 expression in HEK293 cells. The lane on the left is treated with the antigen-specific peptide.
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (Ser698) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
Select
TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
TP53BP2 / ASPP2 Antibody - TP53BP2 Antibody western blot of T47D cell line lysates (35 ug/lane). The TP53BP2 antibody detected the TP53BP2 protein (arrow).
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TP53BP2 / ASPP2 Rabbit anti-Human Polyclonal (aa93-122) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 29 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).