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Anti-TP53BP1 / 53BP1 Antibody (C-Terminus, Biotin) LS-C141098

Ordering

Wt. Vol. Conc. Price
100 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TP53BP1 / 53BP1 Antibodies

Anti-TP53BP1 / 53BP1 Antibody IHC-plus™ LS-B315
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus) IHC-plus™ LS-B1714
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TP53BP1 / 53BP1 Antibody (aa350-400) IHC-plus™ LS-B6175
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Western blot (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human TP53BP1 / 53BP1
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • ICC (1:200 - 1:1000)
  • Western blot (1:200 - 1:10000)
  • (applications tested for the base form of this product only)

Specificity and Use

TP53BP1 / 53BP1 antibody was raised against the epitope recognized by this antibody maps to a region between residues 1925 and the C-terminus (residue 1972) of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158)
C-Terminus
Human 53BP1 protein.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS
Store at 4°C. Do not freeze.
For research use only.

About TP53BP1 / 53BP1

Q12888 NM_005657 NP_005648.1

TP53BP1 Antibody, 53BP1 Antibody, p202 Antibody, p53-binding protein 1 Antibody, p53-binding protein 53bp1 Antibody, p53BP1 Antibody

Tumor protein p53 binding protein 1 binds to the central domain of p53 required for site-specific DNA binding thus inhibiting the ability of p53 to bind DNA. TP53BP1 also functions as a checkpoint protein with properties of a DNA double-strand break sensor. It is a putative substrate of ATM kinase and is phosphorylated in response to DNA damage and localizes to sites of double-strand breaks.

Immunohistochemistry

Immunohistochemistry
Placenta Villi 40X. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry of human 53BP1. Sample: Whole cell lysate (20 ug/lane) from U2Os cells resolved on a 3 to 8% Tris acetate gel. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Western blot of human 53BP1. Sample: Whole cell lysate (20 ug/lane) from U2Os cells resolved on a 3 to 8% Tris acetate gel. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/3/2016

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