Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases.
Western blot of TP53 expression in transfected 293T cell line by TP53 monoclonal antibody (M04), clone 2C11.
TP53 monoclonal antibody (M04), clone 2C11 Western blot of TP53 expression in A-431.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged TP53 is approximately 3 ng/ml as a capture antibody.
Western blot of TP53 over-expressed 293 cell line, cotransfected with TP53 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with TP53 monoclonal antibody, clone 2C11. GAPDH ( 36.1 kD ) used as specificity a.
Requested From: United States
Date Requested: 10/25/2016