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Anti-TOPBP1 Antibody (aa1187-1621) LS-C144235


Wt. Vol. Conc. Price
100 µg - - $650
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TOPBP1 Antibodies

Anti-TOPBP1 Antibody (phospho-Ser1159, PE) LS-C271963
Rabbit Polyclonal (IgG) to Human TOPBP1
ELISA, Dot Blot
PE Conjugated
Anti-TOPBP1 Antibody (aa1114-1142, Biotin) LS-C271966
Rabbit Polyclonal (IgG) to Human TOPBP1
Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human TOPBP1
Western blot


Human TOPBP1
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


Western blot (0.2 µg/ml)

Specificity and Use

TOPBP1 antibody was raised against recombinant corresponding to aa1187-1621 from human TOP2B expressed in E. coli (Q02880)
Human TOP2B.


Lyophilized from PBS, 5% trehalose
Sterile PBS
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
For research use only.

About TOPBP1

Q92547 NM_007027 NP_008958.2

TOPBP1 Antibody, KIAA0259 Antibody, TOP2BP1 Antibody

Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.

Requested From: United States
Date Requested: 10/25/2016

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