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Anti-TOP1 / Topoisomerase I Antibody LS-C108432

Note: This antibody replaces LS-C210472, LS-C108433


Wt. Vol. Conc. Price
- 100 µl - $240
- 500 µl - $360
- 1000 µl - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TOP1 / Topoisomerase I Antibodies

Anti-TOP1 / Topoisomerase I Antibody (clone 1A1) LS-C105043
Mouse Monoclonal [clone 1A1] (IgG1,k) to Human TOP1 / Topoisomerase I
Western blot, ELISA
Enzyme-Linked Immunosorbent Assay Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TOP1 / Topoisomerase I
IHC - Paraffin


Human TOP1 / Topoisomerase I
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified


IHC - Paraffin (1:100)

Specificity and Use

TOP1 / Topoisomerase I antibody was raised against a synthetic peptide derived from internal region of human topoisomerase I protein.
internal region


10mM PBS/1% BSA buffer pH 7.4 with 0.1% sodium azide
Store at 2°C to 8°C degrees. Do not freeze.
For research use only.

About TOP1 / Topoisomerase I

P11387 NM_003286 NP_003277.1

TOP1 Antibody, DNA topoisomerase I Antibody, DNA topoisomerase 1 Antibody, TOPI Antibody, Topoisomerase (DNA) I Antibody, Topoisomerase I Antibody, Type I DNA topoisomerase Antibody

Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.

Immunohistochemistry - Paraffin

Immunohistochemistry - Paraffin
Human, Breast carcinoma: Formalin-Fixed, Paraffin-Embedded (FFPE)

Requested From: United States
Date Requested: 10/24/2016

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