Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified
Applications
IHC (2 µg/ml)
Western blot (1 µg/ml)
Specificity and Use
TOLLIP antibody was raised against synthetic peptide TOLLIP 16 aa near the carboxy terminus of human TOLLIP (Genbank accession No. P60484).
C-Terminus
Recognizes human TOLLIP. Species cross-reactivity: mouse and rat.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1 ug/ml. Immunohistochemistry: 2 ug/ml. Positive control: Rat Brain cell lysate.
Packaging
PBS, pH 7.2, 0.02% sodium azide.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
TOLLIP Antibody, Adapter protein Antibody, IL-1RAcPIP Antibody, Toll interacting protein Antibody, Toll-interacting protein Antibody
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates.