TNPO1 / Transportin 1

transportin 1

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Involved in nuclear import of M9-containing proteins. In vitro, binds directly to the M9 region of the heterogeneous nuclear ribonucleoproteins (hnRNP), A1 and A2 and mediates their nuclear import. Appears also to be involved in hnRNP A1/A2 nuclear export. Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones, and SRP19. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev. Mediates nuclear import of ADAR/ADAR1 (isoform 5) in a RanGTP-dependent manner.

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Products

Antibodies (41)

ELISA Kits (13)

Proteins (4)

Type

Competitive EIA (1)

Primary (41)

Recombinant (4)

Sandwich (10)

Sandwich CLIA (2)

Target

TNPO1 / Transportin 1 (58)

Reactivity

Human (37)

Mouse (26)

Rat (6)

Bovine (8)

Chicken (1)

Cow (8)

Monkey (3)

Porcine (1)

Rabbit (3)

Application

IHC (7)

IHC-P (1)

WB (40)

Flo (7)

ELISA (11)

IF (2)

IP (2)

Peptide-ELISA (1)

Host

rabbit (37)

mouse (3)

rat (1)

Product Group

IHCPlus (1)

Isotype

IgG (11)

IgG1 (2)

IgG1,k (1)

IgG2a (1)

Clonality

monoclonal mc (4)

polyclonal pc (37)

Clone

1D7 (1)

3G2 (1)

D45 (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (9)

APC (3)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (4)

Unconjugated (15)

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Epitope

aa593-836 (8)

aa597-837 (8)

aa626-836 (8)

aa47-74 (7)

Publications

No (58)

Sample Type

Plasma (9)

Serum (9)

Tissue Homogenates (2)

Tag

GST, N-terminus (1)

His (3)

Species

Bovine (1)

Human (2)

Mouse (1)

Source

E. coli (3)

Wheat Germ Extract (1)

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IHC-plus™ TNPO1 / Transportin 1 Antibody (aa47-74) LS-B10559

(4.0) Rating

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$440

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Human TNPO1 / Transportin 1 Protein (Recombinant His) (aa626-836) - LS-G11905

Source:

E. coli

Tag:

His

Molecular Weight:

24.7 kDa

Price:

10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136

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TNPO1 / Transportin 1 Antibody (aa47-74) LS-C325856

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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TNPO1 / Transportin 1 Antibody (aa47-74, Biotin) LS-C271930

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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TNPO1 / Transportin 1 Antibody (aa47-74, FITC) LS-C271931

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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TNPO1 / Transportin 1 Antibody (aa47-74, APC) LS-C271929

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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TNPO1 / Transportin 1 Antibody (aa47-74, Azide-free, HRP) LS-C271932

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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TNPO1 / Transportin 1 Antibody (aa47-74, PE) LS-C271934

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa47-74) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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TNPO1 / Transportin 1 Antibody (clone D45) LS-C82277

Antibody:

TNPO1 / Transportin 1 Mouse anti-Human Monoclonal (D45) Antibody

Reactivity:

Rabbit, Human, Monkey

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$429

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TNPO1 / Transportin 1 Antibody (clone D45) LS-C82235

Antibody:

TNPO1 / Transportin 1 Mouse anti-Human Monoclonal (D45) Antibody

Reactivity:

Rabbit, Human, Monkey

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$482

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Human TNPO1 / Transportin 1 (Sandwich ELISA) ELISA Kit - LS-F27285

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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TNPO1 / Transportin 1 Antibody LS-C660433

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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TNPO1 / Transportin 1 Antibody LS-C779982

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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TNPO1 / Transportin 1 Antibody LS-C803577

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TNPO1 / Transportin 1 Antibody (clone 1D7) LS-C179424

Antibody:

TNPO1 / Transportin 1 Rat anti-Mouse Monoclonal (1D7) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$407

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TNPO1 / Transportin 1 Antibody (clone 3G2) LS-C197584

Antibody:

TNPO1 / Transportin 1 Mouse anti-Human Monoclonal (3G2) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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TNPO1 / Transportin 1 Antibody (aa626-836) LS-C296783

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa626-836) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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TNPO1 / Transportin 1 Antibody (aa626-836, HRP) LS-C706988

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa626-836) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439

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TNPO1 / Transportin 1 Antibody (aa626-836, Biotin) LS-C684274

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa626-836) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

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TNPO1 / Transportin 1 Antibody (aa626-836, FITC) LS-C690488

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa626-836) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$334; 200 µl/$387; 500 µl/$565; 1 ml/$682; 2 ml/$919; 5 ml/$1,549

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TNPO1 / Transportin 1 Antibody (aa626-836, Cy3) LS-C697963

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal (aa626-836) (Cy3) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3

Select

TNPO1 / Transportin 1 Antibody (aa597-837) LS-C296784

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Mouse Polyclonal (aa597-837) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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TNPO1 / Transportin 1 Antibody LS-C771312

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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TNPO1 / Transportin 1 Antibody LS-C410970

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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TNPO1 / Transportin 1 Antibody LS-C749030

Antibody:

TNPO1 / Transportin 1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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