TNKS / Tankyrase

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.

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Products

Antibodies (33)

ELISA Kits (9)

Proteins (1)

Type

Primary (33)

Recombinant (1)

Sandwich (8)

Sandwich CLIA (1)

Target

TNKS / Tankyrase (43)

Reactivity

Human (36)

Mouse (11)

Rat (7)

Bat (6)

Bovine (9)

Chicken (4)

Chimpanzee (9)

Dog (6)

Gibbon (9)

Guinea pig (6)

Horse (6)

Monkey (7)

Pig (9)

Porcine (1)

Rabbit (10)

Sheep (1)

Xenopus (3)

Zebrafish (3)

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Application

IHC (14)

IHC-P (6)

WB (29)

ELISA (13)

IF (2)

IP (2)

Host

rabbit (30)

mouse (1)

goat (1)

rabbit-new zealand white (1)

Product Group

IHCPlus (1)

Isotype

IgG (24)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (32)

Clone

1A2 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (7)

APC Conjugated (1)

Biotin Conjugated (5)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (1)

Unconjugated (16)

Epitope

aa55-82 (7)

aa1079-1128 (4)

aa448-497 (4)

aa972-1021 (4)

C-Terminus (2)

N-Terminus (2)

aa1-50 (1)

aa1270-1320 (1)

aa1277-1327 (1)

Publications

No (43)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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TNKS / Tankyrase Antibody (aa972-1021) LS-B3978

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa972-1021) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

TNKS / Tankyrase Antibody (aa972-1021, HRP) LS-C430087

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa972-1021) (HRP) Antibody

Reactivity:

Xenopus, Pig, Rabbit, Bovine, Human, Chimpanzee, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

TNKS / Tankyrase Antibody (aa972-1021, Biotin) LS-C430083

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa972-1021) (Biotin) Antibody

Reactivity:

Xenopus, Pig, Rabbit, Bovine, Human, Chimpanzee, Gibbon

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TNKS / Tankyrase Antibody (aa972-1021, FITC) LS-C430084

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa972-1021) (FITC) Antibody

Reactivity:

Xenopus, Pig, Rabbit, Bovine, Human, Chimpanzee, Gibbon

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TNKS / Tankyrase Antibody (clone 1A2) LS-C133560

Antibody:

TNKS / Tankyrase Mouse anti-Human Monoclonal (1A2) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

TNKS / Tankyrase Antibody LS-C673605

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

TNKS / Tankyrase Antibody LS-C661143

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

TNKS / Tankyrase Antibody (aa55-82) LS-C325851

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TNKS / Tankyrase Antibody (aa55-82, HRP) LS-C540638

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

200 µl/$952

Select

TNKS / Tankyrase Antibody (aa55-82, Biotin) LS-C520501

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

TNKS / Tankyrase Antibody (aa55-82, FITC) LS-C241982

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TNKS / Tankyrase Antibody (aa55-82, APC) LS-C241983

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TNKS / Tankyrase Antibody (aa55-82, PE) LS-C241984

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

TNKS / Tankyrase Antibody (aa1277-1327) LS-C286108

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa1277-1327) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

TNKS / Tankyrase Antibody (aa55-82) LS-C160090

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa55-82) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

TNKS / Tankyrase Antibody (aa1270-1320) LS-C829446

Antibody:

TNKS / Tankyrase Rabbit-New Zealand White anti-Mouse Polyclonal (aa1270-1320) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

TNKS / Tankyrase Antibody (C-Terminus) LS-C39489

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$801

Select

TNKS / Tankyrase Antibody (C-Terminus) LS-C39493

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

Select

TNKS / Tankyrase Antibody (N-Terminus) LS-C39494

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

Select

TNKS / Tankyrase Antibody LS-C779680

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

TNKS / Tankyrase Antibody (aa1079-1128) LS-C101461

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa1079-1128) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

TNKS / Tankyrase Antibody (aa1079-1128, Biotin) LS-C430086

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa1079-1128) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TNKS / Tankyrase Antibody (aa1079-1128, FITC) LS-C430085

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa1079-1128) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

Select

TNKS / Tankyrase Antibody (N-Terminus) LS-C112766

Antibody:

TNKS / Tankyrase Goat anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$503

Select

TNKS / Tankyrase Antibody (aa1-50) LS-C289149

Antibody:

TNKS / Tankyrase Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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