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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNK2 / ACK1 Antibody (aa161‑175) LS‑C152794
ACK1 antibody LS-C152794 is an unconjugated rabbit polyclonal antibody to ACK1 (TNK2) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C152794-100
100 µl
Unavailable

Popular TNK2 / ACK1 Products

Antibody
Species: Human
Applications: Western blot, ELISA
Dot blot of anti-Phospho-ACK1-pY518 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Species: Human
Applications: Dot Blot
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-TNK2 / ACK1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6360 concentration 1.25 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot

Product Description

ACK1 antibody LS-C152794 is an unconjugated rabbit polyclonal antibody to ACK1 (TNK2) from human, mouse, rat and other species. Validated for WB.
About TNK2 / ACK1
Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Q07912 NM_005781 NP_005772.3

TNK2 Antibody, ACK Antibody, Activated p21cdc42Hs kinase Antibody, Ack kinase Antibody, ACK-1 Antibody, ACK1 Antibody, Activated CDC42 kinase 1 Antibody, p21cdc42Hs Antibody


Specifications

Target
Human TNK2 / ACK1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
TNK2 / ACK1 antibody was raised against kLH-conjugated, synthetic peptide corresponding to amino acids 161-175 (KPDVLSQPEAMDDFI) of human ACK1 Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Guinea pig (100%); Zebra finch (87%); Turkey, Stickleback, Pufferfish (80%).
Epitope
aa161-175
Specificity
ACK1 (Activated cdc42-associated Kinase 1), also known as TNK2 (Tyrosine Kinase, Non-Receptor, 2)
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).
WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).

Western blot

WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).
WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).

Western blot

WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).
WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).

Western blot

WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).
WB: PC-12 cell lysate was probed with anti-ACK1 (1:1000). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates ACK1 (~110 kDa).


Requested From: 
Date Requested: 6/20/2018

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