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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNIP2 / ABIN‑2 Antibody LS‑C11710
ABIN-2 antibody LS-C11710 is an unconjugated rabbit polyclonal antibody to ABIN-2 (TNIP2) from human and mouse. Validated for WB.
Antibody
Catalog
Size
Price
LS-C11710-100
100 µg
$465

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Western blot of recombinant TNIP2 / ABIN-2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Western blot of recombinant TNIP2 / ABIN-2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, Western blot

Product Description

ABIN-2 antibody LS-C11710 is an unconjugated rabbit polyclonal antibody to ABIN-2 (TNIP2) from human and mouse. Validated for WB.

Specifications

Target
Human TNIP2 / ABIN-2
Synonyms
TNIP2, ABIN-2, ABIN2, FLIP1, KLIP, TNFAIP3-interacting protein 2, TNFAIP3 interacting protein 2
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (0.5 - 2 µg/ml)
Immunogen
TNIP2 / ABIN-2 antibody was raised against synthetic peptides of human ABIN-2.
Specificity
Recognizes human ABIN-2. Species cross-reactivity: mouse.
Usage
Suitable for use in Western Blot. Western Blot: 0.5-2 ug/ml. A 66kD band is detected. Positive control: Mouse heart or lung lysate.
Presentation
PBS, 0.05% Sodium Azide, 0.05% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About TNIP2 / ABIN-2
Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. NM_024309


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Requested From: United States
Date Requested: 10/21/2018

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