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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNIP1 Antibody (N‑Terminus, clone 1A11E3) LS‑C11711 Best Seller
TNIP1 antibody LS-C11711 is an unconjugated mouse monoclonal antibody to TNIP1 from human, mouse and rat. Validated for ELISA, IP and WB.
Antibody
Catalog
Size
Price
LS-C11711-100
100 µg (0.5 mg/ml)
$605

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Product Description

TNIP1 antibody LS-C11711 is an unconjugated mouse monoclonal antibody to TNIP1 from human, mouse and rat. Validated for ELISA, IP and WB.
About TNIP1
Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Q15025 NM_006058 NP_006049.3

TNIP1 Antibody, ABIN-1 Antibody, Nef-associated factor 1 Antibody, Nip40-1 Antibody, HVAN Antibody, KIAA0113 Antibody, TNFAIP3-interacting protein 1 Antibody, Nef-associated factor 1 SNP Antibody, HIV-1 Nef-interacting protein Antibody, TNFAIP3 interacting protein 1 Antibody, VAN Antibody


Specifications

Target
Human TNIP1
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [1A11E3]
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
TNIP1 antibody was raised against synthetic peptide derived from the N-terminal region of the human, mouse and rat ABIN-1 protein.
Epitope
N-Terminus
Specificity
Recognizes the ~80kD human ABIN-1 protein. Bands of unknown origin at ~180kD and >250kD were observed in Western Blots using HEK-293 cell lysates. Species sequence homology: mouse and rat 100%.
Usage
Suitable for use in ELISA, Immunoprecipitation and Western Blot. ELISA: 0.1-1 ug/ml. Immunoprecipitation: 7-10 ug/test. Western Blot: 1-3 ug/ml. Positive control: HEK-293 cell lysate.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/16/2018

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