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Anti-TNIP1 Antibody (N-Terminus, clone 1A11E3) LS-C11711

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $530
Inquire for larger quantities

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Mouse Monoclonal [clone 1A11E3] (IgG2a,k) to Human TNIP1
Human, Mouse, Rat
Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human TNIP1
Mouse
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [1A11E3]
Protein A purified

Applications

Western blot (1 - 3 µg/ml), Immunoprecipitation, ELISA (0.1 - 1 µg/ml)

Specificity and Use

TNIP1 antibody was raised against synthetic peptide derived from the N-terminal region of the human, mouse and rat ABIN-1 protein.
N-Terminus
Recognizes the ~80kD human ABIN-1 protein. Bands of unknown origin at ~180kD and >250kD were observed in Western Blots using HEK-293 cell lysates. Species sequence homology: mouse and rat 100%.
Suitable for use in ELISA, Immunoprecipitation and Western Blot. ELISA: 0.1-1 ug/ml. Immunoprecipitation: 7-10 ug/test. Western Blot: 1-3 ug/ml. Positive control: HEK-293 cell lysate.

Packaging

PBS, pH 7.4, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About TNIP1

Q15025 NM_006058 NP_006049.3

TNIP1 Antibody, ABIN-1 Antibody, Nef-associated factor 1 Antibody, Nip40-1 Antibody, HVAN Antibody, KIAA0113 Antibody, TNFAIP3-interacting protein 1 Antibody, Nef-associated factor 1 SNP Antibody, HIV-1 Nef-interacting protein Antibody, TNFAIP3 interacting protein 1 Antibody, VAN Antibody

Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression.

Requested From: United States
Date Requested: 9/28/2016

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