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Anti-TNFSF10 / TRAIL Antibody (aa95-281, clone 2E5, Low Endotoxin) LS-C188227


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TNFSF10 / TRAIL Antibodies

Anti-TNFSF10 / TRAIL Antibody (aa17-35, clone 55B709.3) LS-C493
Mouse Monoclonal [clone 55B709.3] (IgG) to Human TNFSF10 / TRAIL
Western blot
Western blot Image
Anti-TNFSF10 / TRAIL Antibody LS-C18675
Mouse Monoclonal (IgG2b) to Human TNFSF10 / TRAIL
Immunoprecipitation, Flow Cytometry, ELISA
Anti-TNFSF10 / TRAIL Antibody LS-C104433
Mouse Monoclonal (IgG1) to Human TNFSF10 / TRAIL
Western blot, ELISA

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2E5] (IgG1) to Human TNFSF10 / TRAIL
Western blot, Flow Cytometry, Functional Assay
Unconjugated, Low Endotoxin


Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2E5]
Protein A purified
Low Endotoxin


  • Western blot
  • Flow Cytometry
  • Functional Assay

Specificity and Use

TNFSF10 / TRAIL antibody was raised against recombinant human CD253 (TRAIL) aa 95-281.
TRAIL is a cytotoxic protein closely related to Fas (CD95), which induces extensive apoptosis in a range of cell types. TRAIL induces apoptosis via the receptors DR4 and DR5. Most normal tissues are resistant to TRAIL induced apoptosis due to their expression of decoy receptors, DcR1 and DcR2, which antagonize TRAIL activity. TRAIL is expressed by cell lines, activated lymphocytes and on syncytiotrophoblast cells in first trimester pregnancy. Neutralizes TRAIL activity.


Store at -20°C.
For research use only.


P50591 NM_003810 NP_003801.1

TNFSF10 Antibody, Apo-2L Antibody, APO2L Antibody, Apo-2 ligand Antibody, CD253 Antibody, CD253 antigen Antibody, TRAIL Antibody, Protein TRAIL Antibody, TL2 Antibody

TNFSF10 / TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG.

Requested From: United States
Date Requested: 10/27/2016

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