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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF9 / 4‑1BB / CD137 Antibody LS‑C14234
CD137 antibody LS-C14234 is an unconjugated rat monoclonal antibody to mouse CD137 (TNFRSF9 / 4-1BB). Validated for Flow.
Antibody
Catalog
Size
Price
LS-C14234-250
250 µg
$530

Popular TNFRSF9 / 4-1BB / CD137 Products

Antibody
Species: Human
Applications: Immunofluorescence, Flow Cytometry
Antibody
Species: Human
Applications: Flow Cytometry, ELISA, Functional Assay
Antibody
Species: Mouse
Applications: Flow Cytometry, Functional Assay
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry

Product Description

CD137 antibody LS-C14234 is an unconjugated rat monoclonal antibody to mouse CD137 (TNFRSF9 / 4-1BB). Validated for Flow.

Specifications

Target
Mouse TNFRSF9 / 4-1BB / CD137
Synonyms
TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:10 - 1:50)
  • (applications tested for the base form of this product only)
Immunogen
Murine CD137 human Fc fusion protein.
Specificity
Recognizes mouse CD137 (the mouse homologue of human 4-1BB protein).
Usage
Flow Cytometry: 1:10-1:50. Use 10 ul of the suggested working dilution to label 1E6 cells in 100ul.
Presentation
PBS, pH 7.2, 0.1% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About TNFRSF9 / 4-1BB / CD137
TNFRSF9 / 4-1BB / CD137 is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. Q07011 NM_001561 NP_001552.2


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Requested From: United States
Date Requested: 10/16/2018

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