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Anti-TNFRSF6B / DCR3 Antibody (N-Terminus) LS-C187755

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $325
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TNFRSF6B / DCR3 Antibodies

Anti-TNFRSF6B / DCR3 Antibody (clone 7G5) LS-C133572
Mouse Monoclonal [clone 7G5] (IgG2a,k) to Human TNFRSF6B / DCR3
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF6B / DCR3 Antibody (aa29-57, Azide-free, HRP) LS-C271878
Rabbit Polyclonal (IgG) to Human TNFRSF6B / DCR3
Human
IHC, Western blot, Flow Cytometry, ELISA
HRP Conjugated, Azide-free
Anti-TNFRSF6B / DCR3 Antibody (aa29-57, PE) LS-C271879
Rabbit Polyclonal (IgG) to Human TNFRSF6B / DCR3
Human
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TNFRSF6B / DCR3
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Human TNFRSF6B / DCR3
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Ion exchange chromatography
Unmodified

Applications

  • IHC - Paraffin (1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

TNFRSF6B / DCR3 antibody was raised against a peptide corresponding to amino acids near the amino-terminus of human DcR3 precursor.
N-Terminus
Recognizes the amino terminal of human DcR3, otherwise known as Decoy Receptor 3, a 33kD member of the tumor necrosis factor receptor superfamily. DcR3 acts as a receptor for FasL and LIGHT, preventing them from binding to their cell death receptors and thereby inhibiting apoptosis. DcR3 is a soluble decoy receptor found in adult stomach, spinal cord, lymph node, trachea, spleen and lung. It may also be found in fetal lung, brain and liver and is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.

Packaging

PBS, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About TNFRSF6B / DCR3

O95407 NM_032945 NP_003814.1

TNFRSF6B Antibody, Decoy receptor 3 Antibody, DJ583P15.1.1 Antibody, DCR3 Antibody, M68E Antibody, M68 Antibody, TR6 Antibody, Decoy receptor for Fas ligand Antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of human heart with Rabbit anti-Human DcR3

Western blot

Western blot
Western blot of human lysates from heart (H), brain (B) and kidney (K) probed with Rabbit anti-Human DcR3

Requested From: United States
Date Requested: 12/5/2016

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