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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF4 / CD134 / OX40 Antibody (clone OX‑40, Biotin) LS‑C45306
Note: This antibody replaces LS-C62775
Antibody
OX40 antibody LS-C45306 is a biotin-conjugated mouse monoclonal antibody to rat OX40 (TNFRSF4 / CD134). Validated for Flow, IHC and IP.
Catalog
Size
Price
LS-C45306-100
100 µg (0.1 mg/ml)
Unavailable

Popular TNFRSF4 / CD134 / OX40 Products

Antibody
Species: Human
Applications: Flow Cytometry, ELISA
Flow cytometry of TNFRSF4 / CD134 / OX40 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA
Antibody
Species: Human
Applications: Flow Cytometry, ELISA
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

OX40 antibody LS-C45306 is a biotin-conjugated mouse monoclonal antibody to rat OX40 (TNFRSF4 / CD134). Validated for Flow, IHC and IP.
About TNFRSF4 / CD134 / OX40
TNFRSF4 / CD134 / OX40 is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. P43489 NM_003327 NP_003318.1

TNFRSF4 Antibody, ACT35 antigen Antibody, ATC35 antigen Antibody, CD134 Antibody, ACT35 Antibody, OX40 Antibody, OX40 antigen Antibody, OX40L receptor Antibody, OX40 homologue Antibody, CD134 antigen Antibody, OX40 cell surface antigen Antibody, TXGP1L Antibody


Specifications

Target
Rat TNFRSF4 / CD134 / OX40
Host
Mouse
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [OX-40]
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Phytohemagglutinin (PHA) activated rat lymph mode cells.
Specificity
Recognizes the OX40 antigen (CD134), which is present only on activated T lymphocytes that also express CD4. The antigen is a glycoprotein of approximately 50kD molecular weight which is related in sequence to the low affinity Nerve Growth Factor Receptor.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS, 0.09% sodium azide, 1% BSA.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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