Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone JD3] (IgG1,k) to Human TNFRSF25 / DR3
Human TNFRSF25 / DR3
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [JD3]
Specificity and Use
TNFRSF25 / DR3 antibody was raised against human TNFRSF25
The JD3 antibody has been tested by flow cytometric analysis of human peripheral leukocytes and human DR3-transfected cells. It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest.
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
TNFRSF25 / DR3 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins.