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Anti-TNFRSF1B / TNFR2 Antibody (clone 80M2) LS-C18374

Note: This antibody replaces LS-C18378


Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $755
Inquire for larger quantities

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Mouse Monoclonal [clone 80M2] (IgG1) to Human TNFRSF1B / TNFR2
Human, Rat
Immunofluorescence, Immunoprecipitation, Flow Cytometry, ELISA


Human, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [80M2]


  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry (1:10)

Specificity and Use

TNFRSF1B / TNFR2 antibody was raised against tumor Necrosis Factor Receptor 2.
Recognizes the extracellular part of human TNFR2. It also reacts with the soluble receptor. Enhances in vitro TNF responses by increasing the affinity of the soluble form of TNF-alpha to TNF-2. Reactivity with cell bound TNF-Receptor is minimally inhibited by high concentrations of TNF-alpha. Species cross-reactivity: rat.


PBS, pH 7.4, 0.1% BSA.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.


P20333 NM_001066 NP_001057.1

TNFRSF1B Antibody, CD120b antigen Antibody, CD120b Antibody, Etanercept Antibody, p75 TNF receptor Antibody, Soluble TNFR1B variant 1 Antibody, TNFBR Antibody, Tumor necrosis factor receptor Antibody, TNF-R-II Antibody, TNF-R75 Antibody, TNFR2 Antibody, p75TNFR Antibody, p80 TNF-alpha receptor Antibody, TBPII Antibody, TNF-R2 Antibody, TNFR80 Antibody, TNF-RII Antibody, TNFR-II Antibody, TNFR1B Antibody

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Requested From: United States
Date Requested: 10/27/2016

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