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Anti-TNFRSF1B / TNFR2 Antibody (Biotin) LS-C104278

Note: This antibody replaces LS-C54293, LS-C40018

Ordering

Wt. Vol. Conc. Price
25 µg - - $285
50 µg - - $325
Inquire for larger quantities

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Rabbit Polyclonal to Human TNFRSF1B / TNFR2
Human
Western blot, ELISA
Biotin Conjugated

Details

Human TNFRSF1B / TNFR2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Biotin
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (1 µg/ml)

Specificity and Use

TNFRSF1B / TNFR2 antibody was raised against e.coli derived recombinant Human sTNF Receptor II.
Human sTNF Receptor II
ELISA: To detect hsTNF Receptor II by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1 ug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant hsTNF Receptor II. To detect hsTNF Receptor II by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1 ug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with Polyclonal Anti-Human sTNF Receptor II (LS-B7424) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hsTNF Receptor II. Western Blot: To detect hsTNF Receptor II by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hsTNF Receptor II is 1.5-3 ng/lane, under either reducing or non-reducing conditions. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS, pH 7.2
Sterile PBS containing 0.1% BSA
Store Lyophilized at room temperature up to 1 month; Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
For research use only.

About TNFRSF1B / TNFR2

P20333 NM_001066 NP_001057.1

TNFRSF1B Antibody, CD120b antigen Antibody, CD120b Antibody, Etanercept Antibody, p75 TNF receptor Antibody, Soluble TNFR1B variant 1 Antibody, TNFBR Antibody, Tumor necrosis factor receptor Antibody, TNF-R-II Antibody, TNF-R75 Antibody, TNFR2 Antibody, p75TNFR Antibody, p80 TNF-alpha receptor Antibody, TBPII Antibody, TNF-R2 Antibody, TNFR80 Antibody, TNF-RII Antibody, TNFR-II Antibody, TNFR1B Antibody

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Requested From: United States
Date Requested: 12/2/2016

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