Human TNFRSF1B / TNFR2

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Biotin. Also available Unconjugated.

Affinity purified

Unmodified

(PHP215).

Recognizes the soluble form of human CD120b, otherwise known as sTNF receptor type II (sTNFR1I), a member of the tumor necrosis factor receptor (TNFR) superfamily, produced by proteolytic cleavage of the membrane form by the metalloprotease TACE. CD120b plays a key role in regulating the inflammatory response, acting as a receptor for both tumor necrosis factor alpha (TNF-alpha) and TNF-beta, and is also involved in programmed cell death and anti-viral activity. sTNFR1I acts as an inhibitor of TNF-alpha induced responses, by acting as a decoy receptor.

• Western blot (0.1 - 0.2 µg/ml)
• ELISA (0.25 - 1 µg/ml)
• Applications tested for the base form of this product only

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS

Reconstitute in sterile PBS.

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P20333 NCBI: NM_001066 NP_001057.1