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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF1A / TNFR1 Antibody LS‑C104400
Note: This antibody replaces LS-C54291, LS-C40012
TNFR1 antibody LS-C104400 is an unconjugated rabbit polyclonal antibody to human TNFR1 (TNFRSF1A). Validated for ELISA, Neut and WB.
Catalog
Size
Price
LS-C104400-50
50 µg
Unavailable
LS-C104400-100
100 µg
Unavailable

Popular TNFRSF1A / TNFR1 Products

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Product Description

TNFR1 antibody LS-C104400 is an unconjugated rabbit polyclonal antibody to human TNFR1 (TNFRSF1A). Validated for ELISA, Neut and WB.
About TNFRSF1A / TNFR1
TNFRSF1A / TNFR1 is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. P19438 NM_001065 NP_001056.1

TNFRSF1A Antibody, CD120a Antibody, CD120a antigen Antibody, MS5 Antibody, p60 Antibody, TBP1 Antibody, TNF-R55 Antibody, TNFAR Antibody, TNFR1 Antibody, p55-R Antibody, TNF-R Antibody, TNF-R-I Antibody, TNF-R1 Antibody, TNF-RI Antibody, Tnfr Antibody, TNFR-I Antibody, TNFR1-d2 Antibody, TNFR60 Antibody, FPF Antibody, p55 Antibody, Tbpi Antibody, TNFR55 Antibody


Specifications

Target
Human TNFRSF1A / TNFR1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA (0.5 - 2 µg/ml)
  • Neutralization (0.9 - 1.1 µg/ml)
Immunogen
E.coli derived recombinant Human sTNF Receptor I.
Specificity
Human sTNF Receptor-I
Usage
Neutralization: To yield one-half maximal inhibition [ND] of the biological activity of hsTNF-receptor (0.3 ug/ml), a concentration of 0.9-1.1 ug/ml of this antibody is required. ELISA: To detect hsTNF-receptor by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5-2 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human sTNF-receptor (LS-C104403) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hsTNF-receptor. Western Blot: To detect hsTNF-receptor by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hsTNF-receptor is 1.5-3 ng/lane, under either reducing or non-reducing conditions.
Presentation
Lyophilized from PBS, pH 7.2
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Storage
Store Lyophilized at room temperature up to 1 month; Reconstituted for up to 2 weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400
Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400
Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400
Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (non-reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Western blot

Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400
Western Blot (reducing) of TNFRSF1A / TNFR1 antibody LS-C104400

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400
Sandwich ELISA of TNFRSF1A / TNFR1 antibody LS-C104400


Requested From: 
Date Requested: 6/21/2018

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