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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF18 / GITR Antibody LS‑C129245
Antibody
GITR antibody LS-C129245 is an unconjugated rat monoclonal antibody to mouse GITR (TNFRSF18). Validated for Flow.
Catalog
Size
Price
LS-C129245-100
100 µg (1 mg/ml)
Unavailable

Popular TNFRSF18 / GITR Products

Antibody
Species: Human
Applications: Flow Cytometry
Flow cytometry of TNFRSF18 / GITR antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA
Flow cytometry of TNFRSF18 / GITR antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA
Anti-TNFRSF18 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6398 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, ELISA
IHC of paraffin-embedded Human lymphoma tissue using anti-TNFRSF18 mouse monoclonal antibody. (heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

GITR antibody LS-C129245 is an unconjugated rat monoclonal antibody to mouse GITR (TNFRSF18). Validated for Flow.
About TNFRSF18 / GITR
TNFRSF18 / GITR is a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Q9Y5U5 NM_004195 NP_004186.1

TNFRSF18 Antibody, AITR Antibody, CD357 Antibody, CD357 antigen Antibody, GITR Antibody, GITR-D Antibody


Specifications

Target
Mouse TNFRSF18 / GITR
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:50 - 1:100)
  • (applications tested for the base form of this product only)
Immunogen
TNFRSF18 / GITR antibody was raised against nB2/6TG cells transfected with mouse GITR.
Specificity
Recognizes mouse glucocorticoid-induced tumor necrosis factor receptor (mGITR).
Usage
Suitable for use in Flow cytometry: 1:50-1:100; 10 ul labels 10^6 cells in 100ul.
Presentation
PBS, pH 7.4, 0.09% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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