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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF17 / BCMA Antibody (C‑Terminus) LS‑C83463
Antibody
BCMA antibody LS-C83463 is an unconjugated rabbit polyclonal antibody to human BCMA (TNFRSF17). Validated for WB.
Catalog
Size
Price
LS-C83463-100
100 µg
Unavailable

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Product Description

BCMA antibody LS-C83463 is an unconjugated rabbit polyclonal antibody to human BCMA (TNFRSF17). Validated for WB.
About TNFRSF17 / BCMA
TNFRSF17 / BCMA is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. Q02223 NM_001192 NP_001183.2

TNFRSF17 Antibody, B cell maturation antigen Antibody, BCMA Antibody, CD269 antigen Antibody, B-cell maturation factor Antibody, B-cell maturation protein Antibody, BCM Antibody, CD269 Antibody


Specifications

Target
Human TNFRSF17 / BCMA
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (2 - 5 µg/ml)
Immunogen
TNFRSF17 / BCMA antibody was raised against a synthetic peptide corresponding to the carboxy terminus of human BCMA.
Epitope
C-Terminus
Specificity
Recognizes human BCMA (B Cell Maturation Protein). BCMA is a receptor for BAFF and April, two novel members of the TNF superfamily of proteins regulating immune response and the induction of apoptosis through the activation of NF kappaB and c-jun N terminal kinase.
Usage
Western Blot: A band of approximately 27 kD is detected using K562 cell lysate.
Presentation
PBS, pH 7.4, 0.02% sodium azide
Storage
Store at 4°C, stable for 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/25/2018

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