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Anti-TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-4, FITC) LS-C188541


Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $380
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TNFRSF12A / TWEAK Receptor Antibodies

Anti-TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-4) LS-C105966
Mouse Monoclonal [clone ITEM-4] (IgG2b,k) to Human TNFRSF12A / TWEAK Receptor
IHC - Frozen, Western blot, Flow Cytometry
Flow Cytometry Image
Anti-TNFRSF12A / TWEAK Receptor Antibody LS-C150061
Goat Polyclonal (IgG) to Human TNFRSF12A / TWEAK Receptor
IHC, Western blot, ELISA, Neutralization

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone ITEM-4] (IgG2b) to Human TNFRSF12A / TWEAK Receptor
Human, Mouse, Rat
IHC - Frozen, Western blot, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated


Human TNFRSF12A / TWEAK Receptor
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [ITEM-4]
Protein G purified


  • IHC - Frozen
  • Western blot
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

TNFRSF12A / TWEAK Receptor antibody was raised against human CD266 transfected P815 cells.
Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.


PBS, pH 7.4, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About TNFRSF12A / TWEAK Receptor

Q9NP84 NM_016639 NP_057723.1

TNFRSF12A Antibody, CD266 antigen Antibody, CD266 Antibody, FGF-inducible 14 Antibody, FN14 Antibody, Tweak-receptor Antibody, TWEAKR Antibody

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Requested From: United States
Date Requested: 10/24/2016

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