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TNFRSF11A / RANK

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

TNFRSF11A / RANK is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Gene Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF11A, CD265, CD265 antigen, ODFR, LOH18CR1, OPTB7, OSTS, PDB2, RANK, Receptor activator of NF-KB, TRANCER, FEO, OFE
Target Sequences: NM_003839 NP_003830.1 Q9Y6Q6

Publications (2)

1
Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation. Yugo Morita, Motoo Saito, Javier Rangel-Moreno, Anthony M Franchini, John R Owen, John C Martinez, John L Daiss, Karen L de Mesy Bentley, Stephen L Kates, Edward M Schwarz, Gowrishankar Muthukrishnan. Bone research. 2022 August;10:56. [Full Text Article] [PubMed:36028492] [PMC:PMC9418173] Related Antibodies: LS-B2077.
2
Granulomatous Inflammation and Hypercalcemia in Patients With Severe Systemic Oxalosis. Peggy Perrin, Jérome Olagne, Arnaud Delbello, Stanislas Bataille, Laurent Mesnard, Claire Borni, Bruno Moulin, Sophie Caillard. Kidney international reports. 2022 February;7:343-349. [Full Text Article] [PubMed:35155875] [PMC:PMC8820998] Related Antibodies: LS-B11252.

☰ Filters
Antibodies (80)
ELISA Kits (30)
Proteins (19)
Over-Expression Lysate (2)
Primary (80)
Recombinant (17)
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TNFRSF11A / RANK (129)
Human (72)
Mouse (47)
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IHC (14)
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ICC (2)
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rabbit (59)
mouse (15)
rat (6)
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monoclonal mc (21)
polyclonal pc (59)
64C1385.1 (2)
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aa31-214 (8)
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Biologically active (3)
TNFRSF11A / RANK Antibody - Anti-TNFRSF11A / RANK antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa603-613) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF11A / RANK Antibody - Anti-TNFRSF11A / RANK antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF11A / RANK Antibody - Anti-TNFRSF11A / RANK antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
TNFRSF11A / RANK Antibody - Anti-TNFRSF11A / RANK antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (9A725) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TNFRSF11A / RANK Protein - Recombinant Receptor Activator Of Nuclear Factor Kappa B By SDS-PAGE
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E. coli
His, N-Terminal
30.0 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
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TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (Azide-free) (9A725) Antibody
Mouse, Rat, Human
Flo, IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
TNFRSF11A / RANK Antibody - Immunohistochemistry - Anti-RANK Picoband Antibody
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa33-208) (Azide-free) (64C1385.1) Antibody
Mouse, Human
Flo, IP, WB
Unconjugated, Azide-free
0.1 mg/$386
TNFRSF11A / RANK Antibody - Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200.
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa60-120) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TNFRSF11A / RANK Antibody - Immunohistochemistry of paraffin-embedded mouse brain using TNFRSF11A antibody at dilution of 1:100 (20x lens).
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TNFRSF11A / RANK Antibody - Anti-Human sRANK Receptor Western Blot Unreduced
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
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TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (PE) Antibody
Human
Flo
PE Conjugated
100 µl/$836
TNFRSF11A / RANK Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal (aa450-500) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
TNFRSF11A / RANK ELISA Kit
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Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$795
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$795
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$657
TNFRSF11A / RANK Antibody - Intracellular flow analysis of RANK in RAW cells using 0.5 ug of RANK antibody. Green histogram represents isotype control antibody, ; red represents RANK antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TNFRSF11A / RANK Mouse anti-Human Monoclonal (aa326-616) (PE) (9A725) Antibody
Mouse, Human
Flo
PE Conjugated
0.1 ml/$416
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TNFRSF11A / RANK ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Mouse
625 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$479
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HEK 293 Cells
Human IgG1 Fc
Less than 0.01 EU/µg protein (determined by LAL method).
~55kDa (SDS-PAGE)
50 µg/$351
TNFRSF11A / RANK Antibody - Anti-TNFRSF11A rabbit polyclonal antibody at 1:500 dilution. Lane A: 293 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 66 kDa. Observed band size: 98 kDa.
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TNFRSF11A / RANK Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, WB
Unconjugated, Preservative Free
100 µl/$412
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TNFRSF11A / RANK Mouse anti-Human Monoclonal (8H8B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
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TNFRSF11A / RANK Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo, IP
Unconjugated
250 µg/$732
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TNFRSF11A / RANK Rat anti-Mouse Monoclonal (LOB14-8) Antibody
Mouse
ELISA, Flo, IP
Unconjugated
0.25 mg/$453
Viewing 1-25 of 129 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).