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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TNFRSF11A / RANK Antibody (clone R12‑31) LS‑C107079
Antibody
RANK antibody LS-C107079 is an unconjugated rat monoclonal antibody to mouse RANK (TNFRSF11A). Validated for Flow.
Catalog
Size
Price
LS-C107079-50
50 µg
Unavailable
LS-C107079-100
100 µg
Unavailable
LS-C107079-500
500 µg
Unavailable

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Species: Human
Applications: Western blot, ELISA

Product Description

RANK antibody LS-C107079 is an unconjugated rat monoclonal antibody to mouse RANK (TNFRSF11A). Validated for Flow.
About TNFRSF11A / RANK
TNFRSF11A / RANK is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Q9Y6Q6 NM_003839 NP_003830.1

TNFRSF11A Antibody, CD265 Antibody, CD265 antigen Antibody, ODFR Antibody, LOH18CR1 Antibody, OPTB7 Antibody, OSTS Antibody, PDB2 Antibody, RANK Antibody, Receptor activator of NF-KB Antibody, TRANCER Antibody, FEO Antibody, OFE Antibody


Specifications

Target
Mouse TNFRSF11A / RANK
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [R12-31]
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
Human CD265
Usage
The R12-31 antibody has been tested by flow cytometric analysis of mouse RANK transfected cells. This can be used at less than or equal to 1 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Presentation
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Storage
Store at 4°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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