LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-TNFRSF10A / DR4 Antibody (clone 32A1380) IHC-plus™ LS-B2073

Note: This antibody replaces LS-C525

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TNFRSF10A / DR4 Antibodies

Anti-TNFRSF10A / DR4 Antibody IHC-plus™ LS-B604
Rabbit Polyclonal to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10A / DR4 Antibody (clone 32A1380) IHC-plus™ LS-B2073
Mouse Monoclonal [clone 32A1380] (IgG1) to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot, Flow Cytometry, Neutralization
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10A / DR4 Antibody (clone HS101) LS-C344759
Mouse Monoclonal [clone HS101] (IgG1) to Human TNFRSF10A / DR4
Human
ICC, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 32A1380] (IgG1) to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot, Flow Cytometry, Neutralization
Unconjugated

Details

Human TNFRSF10A / DR4
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [32A1380]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (2 - 4 µg/ml)
  • Flow Cytometry
  • Neutralization

Specificity and Use

TNFRSF10A / DR4 antibody was raised against a peptide corresponding to amino acid2 to 21 of human DR4.
A peptide corresponding to amino acid 1 to 20 of human DR4 mature protein.
Immunohistochemistry: LS-B2073 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2073 was determined to be 5 ug/ml.

Packaging

PBS, 0.05% BSA, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About TNFRSF10A / DR4

NM_003844

TNFRSF10A Antibody, APO2 Antibody, CD261 Antibody, DR4 Antibody, TRAIL-R1 Antibody, TRAILR-1 Antibody, TRAILR1 Antibody, TRAIL receptor 1 Antibody, CD261 antigen Antibody, Cytotoxic TRAIL receptor Antibody, Death receptor 4 Antibody

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1.

Immunohistochemistry

Immunohistochemistry
Anti-TNFRSF10A / DR4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2073 concentration 5 ug/ml.

Western blot

Western blot
Western blot of 15 ug of total cell lysate from Daudi cells with anti-DR4 (antibody) at 2 ug/ml.

Requested From: United States
Date Requested: 12/4/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number