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TNFRSF10A / DR4

tumor necrosis factor receptor superfamily, member 10a

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.

Gene Name: tumor necrosis factor receptor superfamily, member 10a
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF10A, APO2, CD261, DR4, TRAIL-R1, TRAILR-1, TRAILR1, TRAIL receptor 1, CD261 antigen, Cytotoxic TRAIL receptor, Death receptor 4
Target Sequences: NM_003844

☰ Filters
Antibodies (88)
Proteins (6)
ELISA Kits (4)
Custom (1)
Primary (88)
Recombinant (6)
Sandwich (3)
TNFRSF10A / DR4 (98)
Human (91)
Mouse (8)
Rat (6)
Chimpanzee (3)
Monkey (1)
IHC (9)
IHC-Fr (1)
IHC-P (4)
WB (57)
Flo (28)
Block (1)
ELISA (24)
Func (11)
ICC (15)
IF (7)
IP (16)
Neut (2)
Peptide-ELISA (2)
rabbit (49)
mouse (39)
Product Group
IHCPlus (3)
IgG (35)
IgG1 (24)
IgG1,k (10)
IgG2b (1)
monoclonal mc (39)
polyclonal pc (49)
11D73 (1)
32A1380 (2)
32A242 (2)
DJR1 (1)
DR-4-02 (5)
HS101 (6)
OTI11B12 (2)
OTI8A12 (2)
TR1.02 (1)
96-Well Microplate (1)
96-Well Strip Plate (3)
APC Conjugated (4)
Atto 488 Conjugated (1)
Atto 647N Conjugated (1)
Azide-free (3)
Biotin Conjugated (8)
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FITC Conjugated (11)
HRP Conjugated (7)
Low Endotoxin (1)
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aa418-446 (7)
aa263-468 (4)
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aa2-21 (2)
370-450 aa, C-terminal (1)
Asp430 (1)
Extracellular Domain (1)
aa105-204 (1)
aa110-125 (1)
aa401-450 (1)
No (96)
Yes (2)
Cell Lysates (1)
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6His, C-terminus (1)
Fc (1)
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Human (6)
E. coli (1)
HEK 293 Cells (1)
Human (1)
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Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (5)
Biologically active (1)
TNFRSF10A / DR4 Antibody - Anti-TNFRSF10A / DR4 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
TNFRSF10A / DR4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
TNFRSF10A / DR4 Antibody - Anti-TNFRSF10A / DR4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TNFRSF10A / DR4 Mouse anti-Human Monoclonal (32A1380 ) Antibody
Human
Flo, IHC, IHC-P, Neut, WB
Unconjugated
50 µg/$460
TNFRSF10A / DR4 Antibody - Human DR4 transfected cells stained with purified DJR1, followed by anti-mouse IgG FITC
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TNFRSF10A / DR4 Mouse anti-Human Monoclonal (Extracellular Domain) (DJR1) Antibody
Human
Flo
Unconjugated
25 µg/$276; 100 µg/$344
TNFRSF10A / DR4 Antibody - Immunofluorescence staining (confocal microscopy) of HeLa human cervix carcinoma cell line transfected with TRAIL-R1 expression plasmid using anti-human TRAIL-R1 (DR-4-02).
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TNFRSF10A / DR4 Mouse anti-Human Monoclonal (DR-4-02) Antibody
Human
Flo, Func, ICC, IP
Unconjugated
100 µg/$337
TNFRSF10A / DR4 Antibody - Anti-TNFRSF10A / DR4 antibody IHC of human small intestine042998.1. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TNFRSF10A / DR4 Mouse anti-Human Monoclonal (32A242) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (Low Endotoxin) (DR-4-02) Antibody
Human
Flo, Func, ICC, IP
Unconjugated, Low Endotoxin
0.1 mg/$337
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (HS101) Antibody
Human
Flo, Func, ICC, IP
Unconjugated
100 µg/$470
TNFRSF10A / DR4 Antibody - Surface staining of CD261-transfected HEK-293 cells with anti-CD261/TRAIL-R1 (DR-4-02) FITC.
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (FITC) (DR-4-02) Antibody
Human
Flo, Func, ICC, IP
FITC Conjugated
0.1 mg/$400
TNFRSF10A / DR4 Antibody - Immunohistochemistry of DR4 in human spleen tissue with DR4 antibody at 5 µg/mL.
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TNFRSF10A / DR4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, WB
Unconjugated
0.1 mg/$460
TNFRSF10A / DR4 Antibody - Immunohistochemistry detection of endogenous TRAIL-R1 in paraffin-embedded human carcinoma tissues (colon, tonsil) using mAb to TRAIL-R1 (TR1.02) .
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (TR1.02) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µg/$470
TNFRSF10A / DR4 Antibody - IHC image of TNFRSF10A Antibody diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
TNFRSF10A / DR4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
TNFRSF10A / DR4 Antibody - Western blot - Anti-DR4 Picoband Antibody
Select
TNFRSF10A / DR4 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (HS101) Antibody
Human
Flo, Func, ICC, IP
Unconjugated
100 µg/$470
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (Biotin) (HS101) Antibody
Human
Flo, Func, ICC, IP
Biotin Conjugated
100 µg/$491
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (FITC) (HS101) Antibody
Human
Flo, Func, ICC, IP
FITC Conjugated
100 Tests/$491
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (Atto 647N) (HS101) Antibody
Human
Flo, Func, ICC, IP
Atto 647N Conjugated
100 Tests/$491
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (Atto 488) (HS101) Antibody
Human
Flo, Func, ICC, IP
Atto 488 Conjugated
100 Tests/$491
TNFRSF10A / DR4 Antibody - Western Blot: TRAIL-R1 Antibody (32A1380) [Azide Free] - Analysis of TRAIL-R1 antibody in Daudi cell lysate using DR4 antibody at 2 ug/ml. Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test. This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (aa2-21) (Azide-free) (32A1380) Antibody
Human
Block, Flo, Neut, WB
Unconjugated, Azide-free
0.1 mg/$386
TNFRSF10A / DR4 Antibody - Surface staining of CD261-transfected HEK-293 cells with anti-CD261/TRAIL-R1 (DR-4-02) PE.
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (PE) (DR-4-02) Antibody
Human
Flo, Func, ICC, IP
PE Conjugated
0.1 mg/$450
TNFRSF10A / DR4 Antibody - Immunofluorescence staining (confocal microscopy) of HeLa human cervix carcinoma cell line transfected with TRAIL-R1 expression plasmid using anti-human TRAIL-R1.
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal (APC) (DR-4-02) Antibody
Human
Flo, Func, ICC, IP
APC Conjugated
0.1 mg/$450
TNFRSF10A / DR4 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
TNFRSF10A / DR4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TNFRSF10A / DR4 Antibody - Western blot of DR4 antibody
Select
TNFRSF10A / DR4 Rabbit anti-Human Polyclonal (370-450 aa, C-terminal) Antibody
Human, Monkey
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TNFRSF10A / DR4 Antibody - Immunohistochemistry of paraffin-embedded human stomach tissue.
Select
TNFRSF10A / DR4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo
Unconjugated
20 µl/$256; 100 µl/$412
Select
TNFRSF10A / DR4 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
100 µg/$649
Viewing 1-25 of 98 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).