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Anti-TNFAIP3 / A20 Antibody (aa375-537) LS-C34774


Wt. Vol. Conc. Price
50 µg - - $560
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TNFAIP3 / A20 Antibodies

Anti-TNFAIP3 / A20 Antibody IHC-plus™ LS-B3849
Goat Polyclonal to Human TNFAIP3 / A20
Human, Monkey, Rabbit
IHC - Paraffin
Immunohistochemistry Image
Anti-TNFAIP3 / A20 Antibody (C-Terminus) IHC-plus™ LS-B4603
Rabbit Polyclonal to Human TNFAIP3 / A20
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human TNFAIP3 / A20
Western blot


Human TNFAIP3 / A20
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal


Western blot

Specificity and Use

TNFAIP3 / A20 antibody was raised against zinc finger domain corresponding to aa 375-537 of human A20.
Recognizes human A20.
Western Blot (1:1000). A20 is a zinc finger protein that renders cells resistant to apoptosis. A20-deficient mice develop severe inflammation and are hyper-responsive to LPS. S. M. O'Reilly & P. N. Moynagh have shown that full length A20 inhibits activation of NF-kB and AP-1 by TLR4 [1]. A20 associates with A20-binding inhibitor of NF-kB (ABIN)-1 and -2 [2-4], which interfere with NF-kB activation upstream of the IKK complex.


PBS, 0.02% sodium azide.
For research use only.

About TNFAIP3 / A20

P21580 NM_006290 NP_006281.1

TNFAIP3 Antibody, A20 Antibody, TNFA1P2 Antibody, TNF alpha-induced protein 3 Antibody, OTUD7C Antibody, Zinc finger protein A20 Antibody

Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways.

Requested From: United States
Date Requested: 10/28/2016

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