Human TNF Alpha

Rabbit

Human, Mouse, Rat (tested or 100% immunogen sequence identity)

Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

KLH-conjugated synthetic peptide from the C-Terminus of human TNF-alpha.

Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.

• IHC (1:1000 - 1:2000)
• Western blot (1:500 - 1:1000)
• ELISA (1:1000 - 1:5000)

PBS, pH 7.4, 2% BSA, 0.09% sodium azide.

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01375 NCBI: NM_000594 NP_000585.2