Chicken TMOD1 / Tropomodulin 1

Mouse

Chicken (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

TRM-17 (Mab17)

Unconjugated

Protein A purified

Unmodified

Recombinant chicken E-Tmod.

N-Terminus

Recognizes an epitope between amino acid residues 6-57 within the N-terminal (NT) region of Tropomodulin 1 (Tmod1), otherwise known as erythrocyte tropomodulin (E-Tmod). Tmod1 is a sarcomeric protein highly expressed by erythrocytes, heart and skeletal muscle, which binds to and caps pointed ends of actin filaments to prevent thin filament elongation. The binding of the N-terminal region of Tmod1 with the actin-binding protein tropomyosin blocks the elongation and depolymerization of actin filaments, contributing to the geometry of the membrane skeleton. Clone TRM-17 functionally inhibits the binding of Tmod1 to tropomyosin.

• Immunofluorescence
• Western blot
• ELISA

PBS, 0.05% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P28289 NCBI: NM_003275 NP_003266.1