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Anti-TMOD1 / Tropomodulin 1 Antibody (N-Terminus, clone TRM-17 (Mab17)) LS-C188596

Ordering

Wt. Vol. Conc. Price
250 µg - 1 mg/ml Unavailable

Most Popular TMOD1 / Tropomodulin 1 Antibodies

Anti-TMOD1 / Tropomodulin 1 Antibody (clone 2C2) LS-C173114
Mouse Monoclonal [clone 2C2] (IgG2b) to Human TMOD1 / Tropomodulin 1
Human, Monkey, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TMOD1 / Tropomodulin 1 Antibody (N-Terminus, clone TRM-17 (Mab17)) LS-C188596
Mouse Monoclonal [clone TRM-17 (Mab17)] (IgG1) to Chicken TMOD1 / Tropomodulin 1
Chicken, Bird, Mammal
Immunofluorescence, Western blot, ELISA, Functional Assay
Unconjugated
Anti-TMOD1 / Tropomodulin 1 Antibody (aa39-138, FITC) LS-C301879
Rabbit Polyclonal (IgG) to Human TMOD1 / Tropomodulin 1
Human
Western blot, ELISA
FITC Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone TRM-17 (Mab17)] (IgG1) to Chicken TMOD1 / Tropomodulin 1
Chicken, Bird, Mammal
Immunofluorescence, Western blot, ELISA, Functional Assay
Unconjugated

Details

Chicken TMOD1 / Tropomodulin 1
Mouse
Chicken, Bird, Mammal (tested or 100% immunogen sequence identity)
Fish, Insect, Reptile (at least 90% immunogen sequence identity)
IgG1 Monoclonal [TRM-17 (Mab17)]
Unconjugated
Protein A purified
Unmodified

Applications

  • Immunofluorescence
  • Western blot
  • ELISA
  • Functional Assay

Specificity and Use

TMOD1 / Tropomodulin 1 antibody was raised against recombinant chicken E-Tmod.
N-Terminus
Recognizes an epitope between amino acid residues 6-57 within the N-terminal (NT) region of Tropomodulin 1 (Tmod1), otherwise known as erythrocyte tropomodulin (E-Tmod). Tmod1 is a sarcomeric protein highly expressed by erythrocytes, heart and skeletal muscle, which binds to and caps pointed ends of actin filaments to prevent thin filament elongation. The binding of the N-terminal region of Tmod1 with the actin-binding protein tropomyosin blocks the elongation and depolymerization of actin filaments, contributing to the geometry of the membrane skeleton. Clone TRM-17 functionally inhibits the binding of Tmod1 to tropomyosin.

Packaging

PBS, 0.05% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About TMOD1 / Tropomodulin 1

P28289 NM_003275 NP_003266.1

TMOD1 Antibody, D9S57E Antibody, E-Tmod Antibody, E-tropomodulin Antibody, Erythrocyte tropomodulin Antibody, ETMOD Antibody, TMOD Antibody, Tropomodulin-1 Antibody, Tropomodulin 1 Antibody

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.

Requested From: 
Date Requested: 3/23/2017

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