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TMEM49

vacuole membrane protein 1

Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 By similarity. Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.

Gene Name: vacuole membrane protein 1
Synonyms: VMP1, TMEM49, TANGO5, Transmembrane protein 49, EPG3, TDC1, Vacuole membrane protein 1
Target Sequences: NM_030938 NP_112200.2 Q96GC9

☰ Filters
Antibodies (29)
ELISA Kits (4)
Proteins (1)
Custom (3)
Primary (29)
Recombinant (1)
Sandwich (1)
TMEM49 (34)
Human (29)
Mouse (7)
Rat (5)
Bovine (4)
Dog (3)
Guinea pig (3)
Horse (3)
Pig (3)
IHC (2)
IHC-P (2)
WB (24)
ELISA (10)
IF (11)
rabbit (29)
IgG (13)
polyclonal pc (29)
96-Well Strip Plate (4)
AP Conjugated (1)
APC Conjugated (2)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (1)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (9)
aa377-406 (7)
Internal (4)
C-Terminus (1)
No (34)
Plasma (2)
Serum (2)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
Select
TMEM49 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
TMEM49 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer at dilution of 1:100
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TMEM49 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
TMEM49 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
TMEM49 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
TMEM49 Antibody - TMEM49 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The TMEM49 antibody detected the TMEM49 protein (arrow).
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) Antibody
Human
WB
Unconjugated
400 µl/$393
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
100 µg/$442
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
TMEM49 Rabbit anti-Human Polyclonal (aa377-406) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
IF, WB
Biotin Conjugated
100 µg/$477
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
IF, WB
FITC Conjugated
100 µg/$473
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (AP) Antibody
Human
IF, WB
AP Conjugated
100 µg/$474
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (PerCP) Antibody
Human
IF, WB
PerCP Conjugated
100 µg/$479
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (APC) Antibody
Human
IF, WB
APC Conjugated
100 µg/$479
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (Atto 390) Antibody
Human
IF, WB
Atto 390 Conjugated
100 µg/$480
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (RPE) Antibody
Human
IF, WB
RPE Conjugated
100 µg/$477
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (Atto 488) Antibody
Human
IF, WB
Atto 488 Conjugated
100 µg/$479
TMEM49 Antibody - Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-VMP1 Polyclonal Antibody. Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Rabbit Anti-VMP1 Polyclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Rabbit ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane, Vacuole Membrane. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) VMP1 Antibody. (D) Composite.
Select
TMEM49 Rabbit anti-Human Polyclonal (Atto 594) Antibody
Human
IF, WB
Atto 594 Conjugated
100 µg/$479
TMEM49 Antibody - Immunofluorescence analysis of NIH/3T3 cells using VMP1 Polyclonal Antibody at dilution of 1:100 (40x lens).Blue: DAPI for nuclear staining.
Select
TMEM49 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
TMEM49 Antibody - Immunochemical staining of human VMP1 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
Select
TMEM49 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
TMEM49 Antibody - Western blot of VMP1 Antibody with human HepG2 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TMEM49 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
WB
Unconjugated
100 µl/$424
TMEM49 Antibody - Western blot analysis of extracts of mouse kidney, using VMP1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
Select
TMEM49 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).