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| Catalog Number | Size | Price |
|---|---|---|
| LS-C108557-0.1 | 0.1 mg (1 mg/ml) | $460 |
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2 of 3
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Polyclonal Rabbit anti‑Human TMEM173 / STING Antibody (IF, WB) LS‑C108557
Polyclonal Rabbit anti‑Human TMEM173 / STING Antibody (IF, WB) LS‑C108557
Antibody:
TMEM173 / STING Rabbit anti-Human Polyclonal Antibody
Application:
ICC, IF, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
TMEM173 / STING Rabbit anti-Human Polyclonal Antibody
Application:
ICC, IF, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
STING antibody LS-C108557 is an unconjugated rabbit polyclonal antibody to STING (TMEM173) from human. It is reactive with human and mouse. Validated for ICC, IF and WB. Cited in 3 publications.
Target
Human TMEM173 / STING
Synonyms
TMEM173 | ERIS | MITA | HSTING | Transmembrane protein 173 | HMITA | Mediator of IRF3 activation | MPYS | NET23 | STING
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Peptide Column Affinity Chromatography
Modifications
Unmodified
Immunogen
A 17 AA synthetic peptide near the C-Terminus of human MPYS. The immunogen is located within aa 260-310 of MPYS.
Applications
- ICC
- Immunofluorescence
- Western blot (1 - 2 µg/ml)
Failed Applications
- IHC - Paraffin
Usage
MPYS antibody can be used for detection of MPYS by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Western Blot: Predicted: 31, 42 kDa Observed: 32 kDa
Presentation
PBS containing 0.02% Sodium Azide
Storage
Store at 4°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
LSBio Ratings
TMEM173 / STING Antibody for ICC, IF/Immunofluorescence, WB/Western LS-C108557 has an LSBio Rating of
Publications (4.2)
Learn more about The LSBio Ratings Algorithm
Publications (3)
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS, Zaver SA, Schenk M, Zeng S, Zhong W, Liu ZJ, Modlin RL, Liu YJ, Cheng G. Nature immunology. 2012 Dec;13:1155-61.
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Zhang Z, Yuan B, Bao M, Lu N, Kim T, Liu YJ. Nature immunology. 2011 Oct;12:959-65.
Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Zhang G, Chan B, Samarina N, Abere B, Weidner-Glunde M, Buch A, Pich A, Brinkmann MM, Schulz TF. Proceedings of the National Academy of Sciences of the United States of America. 2016 113:E1034-43. (ICC; Human)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse
Applications:
Western blot
Reactivity:
Human
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
