TMEM173 / STING

transmembrane protein 173

Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Acts by recognizing and binding cyclic di-GMP (c-di-GMP), a second messenger produced by bacteria, and cyclic GMP-AMP (cGAMP), a messenger produced in response to DNA virus in the cytosol: upon binding of c-di-GMP or cGAMP, autoinhibition is alleviated and TMEM173/STING is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Essential for the induction of IFN-beta in response to human herpes simplex virus 1 (HHV-1) infection.

☰ Filters

Products

Antibodies (81)

Proteins (8)

ELISA Kits (2)

Type

Over-Expression Lysate (2)

Primary (81)

Recombinant (6)

Sandwich (2)

Target

TMEM173 / STING (91)

Reactivity

Human (66)

Mouse (23)

Rat (15)

Monkey (1)

Application

IHC (26)

IHC-P (11)

WB (77)

Flo (19)

ELISA (17)

ICC (1)

IF (4)

IP (1)

Peptide-ELISA (1)

Host

rabbit (61)

mouse (20)

Product Group

IHCPlus (4)

Isotype

IgG (27)

IgG1 (12)

IgG2a (6)

IgG2b (2)

Clonality

monoclonal mc (20)

polyclonal pc (61)

Clone

1A7 (2)

4.00E+12 (1)

4E12 (1)

OTI1A3 (2)

OTI1G5 (2)

OTI2C8 (2)

OTI2C9 (2)

OTI3B10 (2)

OTI4A7 (2)

OTI4H1 (2)

OTI4H8 (2)

more less

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

APC (3)

APC Conjugated (5)

Azide-free (2)

Biotin Conjugated (8)

Carrier-free (10)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (5)

Unconjugated (41)

more less

Epitope

aa311-340 (13)

aa159-373 (8)

aa160-363 (8)

aa160-371 (8)

aa216-265 (4)

aa268-317 (4)

301-350 aa, C-terminal (1)

C-Terminus (1)

aa284-316 (1)

aa310-360 (1)

aa329-379 (1)

more less

Publications

No (89)

Yes (2)

Sample Type

Cell Lysates (2)

Tissue Homogenates (2)

Tag

6His/Sumo,N-terminus (1)

6His-SUMO, N-terminus (1)

His, N-Terminal (2)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

Select

IHC-plus™ TMEM173 / STING Antibody (aa311-340) LS-B9374

(5.0) Rating

(1) Publication(s)

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa311-340) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

TMEM173 / STING Antibody LS-C108557

(4.2) Rating

(3) Publication(s)

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

IHC-plus™ TMEM173 / STING Antibody (clone 1A7) LS-B14497

(4.0) Rating

Antibody:

TMEM173 / STING Mouse anti-Human Monoclonal (1A7) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

IHC-plus™ TMEM173 / STING Antibody (clone 4E12) LS-B13177

(4.0) Rating

Antibody:

TMEM173 / STING Mouse anti-Human Monoclonal (4E12) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

TMEM173 / STING Antibody LS-C332665

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

TMEM173 / STING Antibody (C-Terminus) LS-C354234

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Human TMEM173 / STING Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72857

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42 kDa

Price:

20 µg/$1,107

Select

Rat TMEM173 / STING Protein (Recombinant His-T7) (aa160-363) - LS-G16256

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.9 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

Select

Human TMEM173 / STING Protein (Recombinant His, N-Terminal) (Leu159-Pro373) - LS-G16258

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28.2 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

Select

Mouse TMEM173 / STING Protein (Recombinant His, N-Terminal) (aa160-371) - LS-G26191

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

27.8 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

Select

Human TMEM173 / STING (Sandwich ELISA) ELISA Kit - LS-F39117

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$902

Select

TMEM173 / STING Antibody (clone OTI4H1) LS-C337801

Antibody:

TMEM173 / STING Mouse anti-Human Monoclonal (OTI4H1) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

TMEM173 / STING Antibody (clone OTI3B10) LS-C174097

Antibody:

TMEM173 / STING Mouse anti-Human Monoclonal (OTI3B10) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

TMEM173 / STING Antibody (aa284-316) LS-C407725

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa284-316) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

TMEM173 / STING Antibody (aa216-265) LS-C102283

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa216-265) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

TMEM173 / STING Antibody LS-C802597

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

TMEM173 / STING Antibody (aa311-340, FITC) LS-C241826

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa311-340) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TMEM173 / STING Antibody (aa311-340, APC) LS-C241823

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa311-340) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TMEM173 / STING Antibody (aa311-340, Azide-free, HRP) LS-C247072

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa311-340) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• FITC
• APC
• HRP, Azide-free

• FITC
• APC
• HRP, Azide-free

Select

IHC-plus™ TMEM173 / STING Antibody LS-B16933

(4.0) Rating

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

TMEM173 / STING Antibody (aa310-360) LS-C148616

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa310-360) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF

Format:

Unconjugated

Price:

100 µg/$386

Select

TMEM173 / STING Antibody (aa160-371) LS-C375020

Antibody:

TMEM173 / STING Rabbit anti-Mouse Polyclonal (aa160-371) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

TMEM173 / STING Antibody (aa160-371, APC) LS-C719742

Antibody:

TMEM173 / STING Rabbit anti-Mouse Polyclonal (aa160-371) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

• Unconjugated
• APC

• Unconjugated
• APC

Select

TMEM173 / STING Antibody LS-C679827

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

TMEM173 / STING Antibody (aa159-373) LS-C296779

Antibody:

TMEM173 / STING Rabbit anti-Human Polyclonal (aa159-373) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345

Viewing 1-25 of 91 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.