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Anti-TMEM123 / Porimin Antibody (aa173-188) IHC-plus™ LS-B2072

Note: This antibody replaces LS-C775, LS-C92027

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TMEM123 / Porimin Antibodies

Anti-TMEM123 / Porimin Antibody (aa173-188) IHC-plus™ LS-B2072
Rabbit Polyclonal (IgG) to Human TMEM123 / Porimin
Human, Monkey, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TMEM123 / Porimin Antibody (C-Terminus) LS-C81536
Rabbit Polyclonal (IgG) to Human TMEM123 / Porimin
Human, Monkey
Western blot
Unconjugated
Western blot Image
Anti-TMEM123 / Porimin Antibody (C-Terminus, FITC) LS-C453486
Rabbit Polyclonal (IgG) to Human TMEM123 / Porimin
Human, Chimpanzee, Monkey
Western blot
FITC Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TMEM123 / Porimin
Human, Monkey, Rabbit
IHC - Paraffin, Western blot
Unconjugated

Details

Human TMEM123 / Porimin
Rabbit
Human, Monkey, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Rat, Hamster, Horse, Chicken (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1 - 3 µg/ml)

Specificity and Use

TMEM123 / Porimin antibody was raised against this antibody was generated by immunizing rabbits with a synthetic peptide corresponding to amino acids 173-188 SRRGIRYRTIDEHDAIof human Porimin; GenBank no. AAG2164.1. This sequence is 100% conserved in cow, and 93% conserved in rat, mouse, and chicken. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Rabbit (100%); Mouse, Rat, Hamster, Horse, Chicken (94%).
aa173-188
A synthetic peptide corresponding to amino acids 173-188 SRRGIRYRTIDEHDAI of human Porimin; GenBank no. AAG2164.1. This sequence is 100% conserved in cow, and 93% conserved in rat, mouse, and chicken.
Immunohistochemistry: LS-B2072 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2072 was determined to be 5 ug/ml.

Packaging

PBS, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About TMEM123 / Porimin

Q8N131 NM_052932 NP_443164.2

TMEM123 Antibody, KCT-3 Antibody, KCT3 Antibody, PORMIN Antibody, Transmembrane protein 123 Antibody, Porimin Antibody, Serine/threonine-rich receptor Antibody

TMEM123 / Porimin is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis.

Immunohistochemistry

Immunohistochemistry
Anti-TMEM123 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2072 concentration 5 ug/ml.

Western blot

Western blot
Western blot of Porimin using antibody at 2 ug/ml?dilution against 20 ug/lane of?HL60 cell lysate.

Requested From: United States
Date Requested: 12/7/2016

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