TLR8

toll-like receptor 8

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

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Antibodies (89)

Proteins (8)

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TLR8 (100)

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IHC-plus™ TLR8 Antibody LS-B1421

(5.0) Rating

(1) Publication(s)

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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IHC-plus™ TLR8 Antibody (aa750-850, clone 44C143) LS-B2248

(4.0) Rating

Antibody:

TLR8 Mouse anti-Human Monoclonal (aa750-850) (44C143) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ TLR8 Antibody (Internal) LS-B430

(4.0) Rating

Antibody:

TLR8 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$515

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IHC-plus™ TLR8 Antibody LS-B4699

(4.0) Rating

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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TLR8 Antibody LS-C331494

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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TLR8 Antibody (aa434-463) LS-C161923

Antibody:

TLR8 Rabbit anti-Human Polyclonal (aa434-463) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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TLR8 Antibody (aa750-850, clone 44C143, PE) LS-C148147

Antibody:

TLR8 Mouse anti-Human Monoclonal (aa750-850) (PE) (44C143) Antibody

Reactivity:

Mouse, Human

Applications:

Flo

Format:

PE Conjugated

Price:

0.1 ml/$416

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Human TLR8 Protein (Recombinant 6His, N-terminus) (aa27-827) - LS-G23167

(4.1) Rating

(2) Publication(s)

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

93.4 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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TLR8 Antibody (PE) LS-C10775

Antibody:

TLR8 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

PE Conjugated

Price:

100 µg/$815

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TLR8 Antibody LS-C747976

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Human TLR8 (Sandwich ELISA) ELISA Kit - LS-F5812

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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TLR8 Antibody LS-C114224

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

0.1 mg/$460

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TLR8 Antibody (C-Terminus) LS-C328913

Antibody:

TLR8 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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TLR8 Antibody (C-Terminus, Biotin) LS-C220900

Antibody:

TLR8 Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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TLR8 Antibody (C-Terminus, FITC) LS-C220901

Antibody:

TLR8 Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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TLR8 Antibody (C-Terminus, APC) LS-C220899

Antibody:

TLR8 Rabbit anti-Mouse Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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TLR8 Antibody (C-Terminus, Azide-free, HRP) LS-C220902

Antibody:

TLR8 Rabbit anti-Mouse Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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TLR8 Antibody (C-Terminus, PE) LS-C220903

Antibody:

TLR8 Rabbit anti-Mouse Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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TLR8 Antibody (Internal) LS-C10768

Antibody:

TLR8 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ICC, IHC, WB

Format:

Unconjugated

Price:

100 µg/$649

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TLR8 Antibody LS-C482285

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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IHC-plus™ TLR8 Antibody LS-A11254

Fast Shipping

(4.0) Rating

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ TLR8 Antibody LS-A11248

Fast Shipping

(4.0) Rating

Antibody:

TLR8 Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

TLR8 Antibody (aa32-153, clone OTI4F3) LS-C795314

Antibody:

TLR8 Mouse anti-Human Monoclonal (aa32-153) (OTI4F3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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TLR8 Antibody (aa32-153, clone OTI4F3, Carrier-free) LS-C798763

Antibody:

TLR8 Mouse anti-Human Monoclonal (aa32-153) (Carrier-free) (OTI4F3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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TLR8 Antibody (Azide-free) LS-C783070

Antibody:

TLR8 Mouse anti-Human Monoclonal (Azide-free) Antibody

Reactivity:

Human

Applications:

Flo, IHC

Format:

Unconjugated, Azide-free

Price:

100 µg/$414

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