TLR6

toll-like receptor 6

Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

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Products

Antibodies (60)

ELISA Kits (9)

Proteins (5)

Type

Custom (3)

Development Kit (1)

Over-Expression Lysate (2)

Primary (60)

Recombinant (3)

Sandwich (5)

Target

TLR6 (74)

Reactivity

Human (55)

Mouse (22)

Rat (2)

Application

IHC (24)

IHC-P (8)

WB (45)

Flo (17)

ELISA (23)

ICC (2)

IF (4)

IP (1)

Host

rabbit (46)

mouse (13)

rat (1)

Product Group

DevKit DuoPlus (1)

IHCPlus (2)

Isotype

IgG (25)

IgG1 (6)

IgG1,k (5)

IgG2a (3)

Clonality

monoclonal mc (14)

polyclonal pc (46)

Clone

3B6 (1)

86B1153.2 (3)

ABM1B50 (2)

TLR6.127 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (7)

Antibody Pair and Standard (1)

APC (2)

APC Conjugated (4)

Azide-free (3)

Biotin Conjugated (7)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (10)

HRP Conjugated (6)

PE Conjugated (6)

Unconjugated (23)

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Epitope

aa17-239 (8)

aa608-796 (8)

aa393-423 (7)

aa722-753 (7)

aa408-424 (3)

aa 280-512 (2)

Internal (1)

aa1-30 (1)

aa25-39 (1)

Publications

No (73)

Yes (1)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Plasma (3)

Serum (3)

Tissue Homogenates (4)

Tag

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (3)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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IHC-plus™ TLR6 Antibody LS-B1419

(4.0) Rating

Antibody:

TLR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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TLR6 Antibody LS-C39747

(4.0) Rating

(1) Publication(s)

Antibody:

TLR6 Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µg/$884

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IHC-plus™ TLR6 Antibody LS-B602

(4.0) Rating

Antibody:

TLR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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TLR6 Antibody (aa408-424, clone 86B1153.2, PE) LS-C148129

Antibody:

TLR6 Mouse anti-Human Monoclonal (aa408-424) (PE) (86B1153.2) Antibody

Reactivity:

Human

Applications:

Flo

Format:

PE Conjugated

Price:

0.1 ml/$416

Select

TLR6 Antibody LS-C10750

Antibody:

TLR6 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$523

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TLR6 Antibody (aa393-423) LS-C98277

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

TLR6 Antibody (aa393-423) LS-C325750

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TLR6 Antibody (aa393-423, Biotin) LS-C217975

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa393-423, FITC) LS-C217976

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa393-423, APC) LS-C217974

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa393-423, PE) LS-C217978

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa393-423, Azide-free, HRP) LS-C217977

Antibody:

TLR6 Rabbit anti-Human Polyclonal (aa393-423) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

TLR6 Antibody LS-C376809

Antibody:

TLR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

Human TLR6 Protein (Recombinant His-T7) (aa608-796) - LS-G12621

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.5 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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TLR6 Antibody (aa722-753) LS-C98279

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

TLR6 Antibody LS-C126385

Antibody:

TLR6 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IF, IP

Format:

Unconjugated

Price:

100 µg/$725

Select

TLR6 Antibody (aa722-753) LS-C330702

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TLR6 Antibody (aa722-753, Biotin) LS-C220881

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa722-753, FITC) LS-C220882

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa722-753, APC) LS-C220880

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa722-753, PE) LS-C220885

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

TLR6 Antibody (aa722-753, Azide-free, HRP) LS-C220884

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa722-753) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

TLR6 Antibody (aa1-30) LS-C98278

Antibody:

TLR6 Rabbit anti-Mouse Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

TLR6 Antibody (FITC) LS-C126387

Antibody:

TLR6 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

FITC Conjugated

Price:

100 µg/$717

Select

TLR6 Antibody (aa 280-512, clone ABM1B50) LS-C760420

Antibody:

TLR6 Mouse anti-Human Monoclonal (aa 280-512) (ABM1B50) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$477

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