Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
TLR5 antibody was raised against synthetic peptide derived from the C-terminal region of the human TLR5 protein.
Reacts with the human TLR5 protein. On Western blots, it identifies a band at ~80-90kD. Reactivity has been confirmed with human BC-1 B-lymphocyte lymphoma, Nalm-6 pre-B lymphocyte, REH pre-B lymphocyte and HEP-G2 hepatocellular carcinoma cell lysates.
Suitable for use in ELISA and Western Blot. Western Blot: 1-3 ug/ml. ELISA: 0.1-1 ug/ml.
PBS, pH 7.4, 0.1% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
TLR5 is a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor.