Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Protein G purified
TLR4 antibody was raised against ba/F3 cell line expressing human TLR4 cell surface antigen, consisting of 799 amino acids. Molecular weight: 88kD.
Recognizes human TLR4 (Toll Like Receptor 4).
Suitable for use in Immunoprecipitation, Neutralization, Flow Cytometry and Confocal Microscopy. Flow Cytometry: 2-5 ug/1 x 1E6 cells. Positive control: ThP1 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.02% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.